Dimenhydrinate and Muscle rigidity - a phase IV clinical study of FDA data

Summary:

Muscle rigidity is reported as a side effect among people who take Dimenhydrinate (dimenhydrinate), especially for people who are female, 60+ old, also take Lorazepam, and have Depression.

The phase IV clinical study analyzes which people have Muscle rigidity when taking Dimenhydrinate. It is created by eHealthMe based on reports of 6,546 people who have side effects when taking Dimenhydrinate from the FDA, and is updated regularly.

What is Dimenhydrinate?

Dimenhydrinate has active ingredients of dimenhydrinate. It is often used in nausea. eHealthMe is studying from 6,644 Dimenhydrinate users. Check the latest studies of Dimenhydrinate.

What is Muscle rigidity?

Muscle rigidity (muscle stiffness) is found to be associated with 786 drugs and 1,035 conditions by eHealthMe. Check the latest studies of Muscle rigidity.

On Jul, 15, 2026

6,546 people reported to have side effects when taking Dimenhydrinate.
Among them, 12 people (0.18%) have Muscle rigidity.

Could Dimenhydrinate cause Muscle rigidity?

Among these 12 people:

What is the gender of people who have Muscle rigidity when taking Dimenhydrinate? *

female: 100 %
male: 0.0 %

What is the age of people who have Muscle rigidity when taking Dimenhydrinate? *

What are other drugs people take besides Dimenhydrinate? *

What are other side effects people have besides Muscle rigidity? *

Visual Impairment: 5 people, 41.67%
Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time): 5 people, 41.67%
Clonus (series of involuntary, rhythmic, muscular contractions and relaxations): 5 people, 41.67%
Confusional State: 5 people, 41.67%
Fever: 5 people, 41.67%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 5 people, 41.67%
Acute Myocardial Infarction (acute heart attack): 5 people, 41.67%
Speech Disorder: 5 people, 41.67%
Loss Of Consciousness: 4 people, 33.33%
Posterior Reversible Encephalopathy Syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss): 4 people, 33.33%

What are the existing conditions these people have? *

Depression: 5 people, 41.67%
Lung Neoplasm Malignant (cancer tumour of lung): 4 people, 33.33%
Renal Colic (renal pain): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Dimenhydrinate and have Muscle rigidity?

- Check whether Muscle rigidity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dimenhydrinate:

Dimenhydrinate (6,644 reports)

Muscle rigidity treatments and more:

Muscle rigidity (16,888 reports)

Browse all side effects of Dimenhydrinate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Muscle rigidity:

Muscle rigidity (786 drugs)

Browse all the conditions that are associated with Muscle rigidity:

Muscle rigidity (1,035 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on dimenhydrinate (the active ingredients of Dimenhydrinate) and Dimenhydrinate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.