Dimetapp and Mitral valve incompetence - a phase IV clinical study of FDA data

Summary:

Mitral valve incompetence is reported as a side effect among people who take Dimetapp (brompheniramine maleate; phenylpropanolamine hydrochloride), especially for people who are female, 50-59 old, also take Contac, and have Depression.

The phase IV clinical study analyzes which people have Mitral valve incompetence when taking Dimetapp. It is created by eHealthMe based on reports of 4,625 people who have side effects when taking Dimetapp from the FDA, and is updated regularly.

What is Dimetapp?

Dimetapp has active ingredients of brompheniramine maleate; phenylpropanolamine hydrochloride. It is often used in cough. eHealthMe is studying from 4,740 Dimetapp users. Check the latest studies of Dimetapp.

What is Mitral valve incompetence?

Mitral valve incompetence (inefficient heart valve) is found to be associated with 1,441 drugs and 1,278 conditions by eHealthMe. Check the latest studies of Mitral valve incompetence.

On Jul, 27, 2026

4,625 people reported to have side effects when taking Dimetapp.
Among them, 30 people (0.65%) have Mitral valve incompetence.

Could Dimetapp cause Mitral valve incompetence?

Among these 30 people:

What is the gender of people who have Mitral valve incompetence when taking Dimetapp? *

female: 83.33 %
male: 16.67 %

What is the age of people who have Mitral valve incompetence when taking Dimetapp? *

What are other drugs people take besides Dimetapp? *

What are other side effects people have besides Mitral valve incompetence? *

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 13 people, 43.33%
Cardiac Failure Congestive: 11 people, 36.67%
Aortic Valve Incompetence: 9 people, 30.00%
Tricuspid Valve Incompetence (inefficient heart valve): 9 people, 30.00%
Cerebral Infarction (less blood supply to brain resulting tissue damage): 7 people, 23.33%
High Blood Pressure: 6 people, 20.00%
Heart Attack: 5 people, 16.67%
Pericardial Effusion (fluid around the heart): 5 people, 16.67%
Right Ventricular Hypertrophy (right ventricular enlargement): 5 people, 16.67%
Skin Discoloration - Bluish (bluish colour of skin): 5 people, 16.67%

What are the existing conditions these people have? *

Depression: 5 people, 16.67%
Nasopharyngitis (inflammation of the nasopharynx): 4 people, 13.33%
Sinus Headache (headache caused by sinus infections): 2 people, 6.67%
The Flu (the flu is caused by an influenza virus): 1 person, 3.33%
Birth Control: 1 person, 3.33%

* Approximation only. Some reports may have incomplete information.

Do you take Dimetapp and have Mitral valve incompetence?

- Check whether Mitral valve incompetence is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dimetapp:

Dimetapp (4,740 reports)

Mitral valve incompetence treatments and more:

Mitral valve incompetence (20,804 reports)

How severe was Mitral valve incompetence and when was it recovered:

Mitral valve incompetence in Dimetapp

Expand to all the drugs that have ingredients of brompheniramine maleate; phenylpropanolamine hydrochloride:

Mitral valve incompetence and drugs with ingredients of brompheniramine maleate; phenylpropanolamine hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Dimetapp:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mitral valve incompetence:

Mitral valve incompetence (1,441 drugs)

Browse all the conditions that are associated with Mitral valve incompetence:

Mitral valve incompetence (1,278 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on brompheniramine maleate; phenylpropanolamine hydrochloride (the active ingredients of Dimetapp) and Dimetapp (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.