Diovan and Hepatotoxicity aggravated - a phase IV clinical study of FDA data

Summary:

Hepatotoxicity aggravated is reported as a side effect among people who take Diovan (valsartan), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Arava, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Hepatotoxicity aggravated when taking Diovan. It is created by eHealthMe based on reports of 80,750 people who have side effects when taking Diovan from the FDA, and is updated regularly.

What is Diovan?

Diovan has active ingredients of valsartan. It is often used in high blood pressure. eHealthMe is studying from 83,153 Diovan users. Check the latest studies of Diovan.

What is Hepatotoxicity aggravated?

Hepatotoxicity aggravated (serious chemical-driven liver damage) is found to be associated with 926 drugs and 411 conditions by eHealthMe. Check the latest studies of Hepatotoxicity aggravated.

On Jul, 08, 2026

80,750 people reported to have side effects when taking Diovan.
Among them, 46 people (0.06%) have Hepatotoxicity aggravated.

Could Diovan cause Hepatotoxicity aggravated?

Among these 46 people:

How long have people been on Diovan when they have Hepatotoxicity aggravated? *

What is the gender of people who have Hepatotoxicity aggravated when taking Diovan? *

female: 62.79 %
male: 37.21 %

What is the age of people who have Hepatotoxicity aggravated when taking Diovan? *

What are other drugs people take besides Diovan? *

What are other side effects people have besides Hepatotoxicity aggravated? *

Abdominal Pain: 15 people, 32.61%
Fatigue (feeling of tiredness): 13 people, 28.26%
Hepatic Enzyme Increased: 12 people, 26.09%
Aspartate Aminotransferase Increased: 11 people, 23.91%
Diarrhea: 10 people, 21.74%
Alanine Aminotransferase Increased: 10 people, 21.74%
Fall: 10 people, 21.74%
Joint Swelling: 10 people, 21.74%
Pain: 10 people, 21.74%
Back Pain: 10 people, 21.74%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 9 people, 19.57%
Pain: 5 people, 10.87%
High Blood Cholesterol: 4 people, 8.70%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 6.52%
Arthritis Bacterial (form of joint disorder that involves inflammation of one or more joints due to bacterial infection): 3 people, 6.52%
Psoriasis (immune-mediated disease that affects the skin): 3 people, 6.52%
Cardiac Disorder: 3 people, 6.52%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 4.35%
Sleep Disorder: 2 people, 4.35%
Thrombocytopenia (decrease of platelets in blood): 1 person, 2.17%

* Approximation only. Some reports may have incomplete information.

Do you take Diovan and have Hepatotoxicity aggravated?

- Check whether Hepatotoxicity aggravated is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Diovan:

Diovan (83,153 reports)

Browse all side effects of Diovan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatotoxicity aggravated:

Hepatotoxicity aggravated (926 drugs)

Browse all the conditions that are associated with Hepatotoxicity aggravated:

Hepatotoxicity aggravated (411 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on valsartan (the active ingredients of Diovan) and Diovan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.