Diphenhydramine hydrochloride and Blood immunoglobulin g decreased - a phase IV clinical study of FDA data

Summary:

Blood immunoglobulin g decreased is reported as a side effect among people who take Diphenhydramine hydrochloride (diphenhydramine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Acetaminophen, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Blood immunoglobulin g decreased when taking Diphenhydramine hydrochloride. It is created by eHealthMe based on reports of 24,692 people who have side effects when taking Diphenhydramine hydrochloride from the FDA, and is updated regularly.

What is Diphenhydramine hydrochloride?

Diphenhydramine hydrochloride has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. eHealthMe is studying from 26,097 Diphenhydramine hydrochloride users. Check the latest studies of Diphenhydramine hydrochloride.

What is Blood immunoglobulin g decreased?

Blood immunoglobulin g decreased is found to be associated with 380 drugs and 364 conditions by eHealthMe. Check the latest studies of Blood immunoglobulin g decreased.

On Aug, 02, 2026

24,692 people reported to have side effects when taking Diphenhydramine hydrochloride.
Among them, 72 people (0.29%) have Blood immunoglobulin g decreased.

Could Diphenhydramine hydrochloride cause Blood immunoglobulin g decreased?

Among these 72 people:

How long have people been on Diphenhydramine hydrochloride when they have Blood immunoglobulin g decreased? *

What is the gender of people who have Blood immunoglobulin g decreased when taking Diphenhydramine hydrochloride? *

female: 80.85 %
male: 19.15 %

What is the age of people who have Blood immunoglobulin g decreased when taking Diphenhydramine hydrochloride? *

What are other drugs people take besides Diphenhydramine hydrochloride? *

What are other side effects people have besides Blood immunoglobulin g decreased? *

Nausea (feeling of having an urge to vomit): 45 people, 62.50%
Weight Decreased: 40 people, 55.56%
The Flu (the flu is caused by an influenza virus): 33 people, 45.83%
Joint Pain: 33 people, 45.83%
Infusion Related Reaction: 32 people, 44.44%
High Blood Pressure: 31 people, 43.06%
Weakness: 29 people, 40.28%
Diarrhea: 27 people, 37.50%
Joint Swelling: 27 people, 37.50%
Pain: 27 people, 37.50%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 35 people, 48.61%
Infection: 14 people, 19.44%
Immunodeficiency Common Variable: 13 people, 18.06%
Seasonal Allergy (allergic condition due to certain season): 10 people, 13.89%
Primary Immunodeficiency Syndrome: 9 people, 12.50%
Headache (pain in head): 5 people, 6.94%
Pain: 4 people, 5.56%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 3 people, 4.17%
High Blood Pressure: 3 people, 4.17%
Birth Control: 3 people, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Diphenhydramine hydrochloride and have Blood immunoglobulin g decreased?

- Check whether Blood immunoglobulin g decreased is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Diphenhydramine hydrochloride:

Diphenhydramine hydrochloride (26,097 reports)

Browse all side effects of Diphenhydramine hydrochloride:

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Browse all the drugs that are associated with Blood immunoglobulin g decreased:

Blood immunoglobulin g decreased (380 drugs)

Browse all the conditions that are associated with Blood immunoglobulin g decreased:

Blood immunoglobulin g decreased (364 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on diphenhydramine hydrochloride (the active ingredients of Diphenhydramine hydrochloride) and Diphenhydramine hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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