Divigel and Lightheadedness - a phase IV clinical study of FDA data

Summary:

Lightheadedness is reported as a side effect among people who take Divigel (estradiol), especially for people who are female, 30-39 old, have been taking the drug for < 1 month also take Vitamin B12, and have Narcolepsy.

The phase IV clinical study analyzes which people have Lightheadedness when taking Divigel. It is created by eHealthMe based on reports of 840 people who have side effects when taking Divigel from the FDA, and is updated regularly.

What is Divigel?

Divigel has active ingredients of estradiol. It is often used in menopause. eHealthMe is studying from 894 Divigel users. Check the latest studies of Divigel.

What is Lightheadedness?

Lightheadedness (a common and often unpleasant sensation of dizziness and/or feeling that one may be about to faint) is found to be associated with 3,964 drugs and 5,781 conditions by eHealthMe. Check the latest studies of Lightheadedness.

On Apr, 18, 2026

840 people reported to have side effects when taking Divigel.
Among them, 30 people (3.57%) have Lightheadedness.

Among these 30 people:

How long have people been on Divigel when they have Lightheadedness? *

What is the gender of people who have Lightheadedness when taking Divigel? *

female: 100 %
male: 0.0 %

What is the age of people who have Lightheadedness when taking Divigel? *

What are other drugs people take besides Divigel? *

What are other side effects people have besides Lightheadedness? *

Stress And Anxiety: 8 people, 26.67%
Ovarian Cysts (fluid filled sacs of the ovary): 8 people, 26.67%
Insomnia (sleeplessness): 8 people, 26.67%
Ovarian Remnant Syndrome (a mass and regular pelvic pain in ovary): 8 people, 26.67%
Otitis (ear infection): 8 people, 26.67%
Muscle Strain (an injury to a muscle in which the muscle fibres tear): 7 people, 23.33%
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve): 7 people, 23.33%
Pain: 5 people, 16.67%
High Blood Pressure: 4 people, 13.33%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 4 people, 13.33%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 26.67%
Seizure Cluster (small group of seizure): 1 person, 3.33%
Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands): 1 person, 3.33%
Rosacea (a skin condition that causes facial redness): 1 person, 3.33%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 3.33%
Meniere's Disease (a disorder of the inner ear that can affect hearing and balance to a varying degree): 1 person, 3.33%
Lung Cancer - Non-Small Cell (lung cancer): 1 person, 3.33%
Localised Infection (infection at the single location): 1 person, 3.33%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 3.33%
Hypersensitivity: 1 person, 3.33%

* Approximation only. Some reports may have incomplete information.

Do you take Divigel and have Lightheadedness?

- Check whether Lightheadedness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Divigel:

Divigel (894 reports)

Lightheadedness treatments and more:

Lightheadedness (613,956 reports)

Browse all side effects of Divigel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lightheadedness:

Lightheadedness (3,964 drugs)

Browse all the conditions that are associated with Lightheadedness:

Lightheadedness (5,781 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on estradiol (the active ingredients of Divigel) and Divigel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.