Docetaxel and Progressive multifocal leukoencephalopathy - a phase IV clinical study of FDA data

Summary:

Progressive multifocal leukoencephalopathy is reported as a side effect among people who take Docetaxel (docetaxel), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Fluorouracil, and have Breast cancer.

The phase IV clinical study analyzes which people have Progressive multifocal leukoencephalopathy when taking Docetaxel. It is created by eHealthMe based on reports of 79,811 people who have side effects when taking Docetaxel from the FDA, and is updated regularly.

What is Docetaxel?

Docetaxel has active ingredients of docetaxel. eHealthMe is studying from 79,875 Docetaxel users. Check the latest studies of Docetaxel.

What is Progressive multifocal leukoencephalopathy?

Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells) is found to be associated with 595 drugs and 921 conditions by eHealthMe. Check the latest studies of Progressive multifocal leukoencephalopathy.



On Jul, 04, 2026

79,811 people reported to have side effects when taking Docetaxel.
Among them, 39 people (0.05%) have Progressive multifocal leukoencephalopathy.

Could Docetaxel cause Progressive multifocal leukoencephalopathy?

Among these 39 people:

How long have people been on Docetaxel when they have Progressive multifocal leukoencephalopathy? *

  • < 1 month: 11.11 %
  • 1 - 6 months: 77.78 %
  • 6 - 12 months: 11.11 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Progressive multifocal leukoencephalopathy when taking Docetaxel? *

  • female: 44.74 %
  • male: 55.26 %

What is the age of people who have Progressive multifocal leukoencephalopathy when taking Docetaxel? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 21.62 %
  • 60+: 78.38 %

What are other drugs people take besides Docetaxel? *

  1. Fluorouracil: 30 people, 76.92%
  2. Letrozole: 17 people, 43.59%
  3. Cyclophosphamide: 17 people, 43.59%
  4. Neulasta: 13 people, 33.33%
  5. Cisplatin: 8 people, 20.51%
  6. Dexamethasone: 8 people, 20.51%
  7. Paclitaxel: 6 people, 15.38%
  8. Oxaliplatin: 6 people, 15.38%
  9. Mirtazapine: 6 people, 15.38%
  10. Mefloquine: 6 people, 15.38%

What are other side effects people have besides Progressive multifocal leukoencephalopathy? *

  1. Jc Virus Infection: 12 people, 30.77%
  2. Lymphopenia (an abnormally low level of lymphocytes in the blood): 8 people, 20.51%
  3. Infection Reactivation: 6 people, 15.38%
  4. Consciousness - Decreased: 5 people, 12.82%
  5. Leukopenia (less number of white blood cells in blood): 5 people, 12.82%
  6. Affect Lability (emotional incontinence): 2 people, 5.13%
  7. Central Nervous System Lesion (an abnormality in tissue of brain or spinal cord): 2 people, 5.13%
  8. Nuclear Magnetic Resonance Imaging Brain Abnormal: 2 people, 5.13%
  9. Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 2 people, 5.13%
  10. Memory Loss: 2 people, 5.13%

What are the existing conditions these people have? *

  1. Breast Cancer: 14 people, 35.90%
  2. Hypopharyngeal Cancer: 8 people, 20.51%
  3. Psoriasis (immune-mediated disease that affects the skin): 7 people, 17.95%
  4. Oesophageal Carcinoma (cancer tumour of oesophagus): 5 people, 12.82%
  5. Metastases To Bone Marrow (cancer spreads to bone marrow): 5 people, 12.82%
  6. Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue): 5 people, 12.82%
  7. Prostate Cancer: 2 people, 5.13%
  8. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 5.13%
  9. Oesophageal Adenocarcinoma (a cancer tumour of an epithelium in oesophagus): 1 person, 2.56%
  10. Oedema (fluid collection in tissue): 1 person, 2.56%

* Approximation only. Some reports may have incomplete information.

Do you take Docetaxel and have Progressive multifocal leukoencephalopathy?

- Check whether Progressive multifocal leukoencephalopathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Docetaxel:

Progressive multifocal leukoencephalopathy treatments and more:

How severe was Progressive multifocal leukoencephalopathy and when was it recovered:

Expand to all the drugs that have ingredients of docetaxel:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Docetaxel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Progressive multifocal leukoencephalopathy:

Browse all the conditions that are associated with Progressive multifocal leukoencephalopathy:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on docetaxel (the active ingredients of Docetaxel) and Docetaxel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: