Dofetilide and Cardiac failure aggravated - a phase IV clinical study of FDA data

Summary:

Cardiac failure aggravated is reported as a side effect among people who take Dofetilide (dofetilide), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Eliquis, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Cardiac failure aggravated when taking Dofetilide. It is created by eHealthMe based on reports of 2,616 people who have side effects when taking Dofetilide from the FDA, and is updated regularly.

What is Dofetilide?

Dofetilide has active ingredients of dofetilide. eHealthMe is studying from 2,646 Dofetilide users. Check the latest studies of Dofetilide.

What is Cardiac failure aggravated?

Cardiac failure aggravated is found to be associated with 1,818 drugs and 760 conditions by eHealthMe. Check the latest studies of Cardiac failure aggravated.

On Jul, 04, 2026

2,616 people reported to have side effects when taking Dofetilide.
Among them, 19 people (0.73%) have Cardiac failure aggravated.

Could Dofetilide cause Cardiac failure aggravated?

Among these 19 people:

How long have people been on Dofetilide when they have Cardiac failure aggravated? *

What is the gender of people who have Cardiac failure aggravated when taking Dofetilide? *

female: 35.29 %
male: 64.71 %

What is the age of people who have Cardiac failure aggravated when taking Dofetilide? *

What are other drugs people take besides Dofetilide? *

Apixaban: 3 people, 15.79%
Furosemide: 3 people, 15.79%
Eliquis: 3 people, 15.79%
Vyndamax: 2 people, 10.53%
Coumadin: 2 people, 10.53%
Pantoprazole: 2 people, 10.53%
Paxil: 2 people, 10.53%
Zofran: 1 person, 5.26%
Clopidogrel: 1 person, 5.26%
Ivabradine Hydrochloride: 1 person, 5.26%

What are other side effects people have besides Cardiac failure aggravated? *

Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 31.58%
Electrocardiogram Qt Prolonged: 4 people, 21.05%
Fainting (loss of consciousness and postural tone): 3 people, 15.79%
Dyspnea (difficult or laboured breathing): 3 people, 15.79%
Pneumonia: 2 people, 10.53%
Muscle Spasms (muscle contraction): 2 people, 10.53%
Acute Kidney Failure: 2 people, 10.53%
Fatigue (feeling of tiredness): 2 people, 10.53%
Weakness: 2 people, 10.53%
Staphylococcal Infection (an infection with staphylococcus bacteria): 2 people, 10.53%

What are the existing conditions these people have? *

Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 8 people, 42.11%
Sinus Rhythm (normal beating of the heart): 2 people, 10.53%
Cardiac Amyloidosis (protein deposition in heart): 2 people, 10.53%
Breast Cancer: 2 people, 10.53%
Amyloidosis (a tumour within which amyloid is produced): 2 people, 10.53%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 1 person, 5.26%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 5.26%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 5.26%
Muscle Spasms (muscle contraction): 1 person, 5.26%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Dofetilide and have Cardiac failure aggravated?

- Check whether Cardiac failure aggravated is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dofetilide:

Dofetilide (2,646 reports)

Browse all side effects of Dofetilide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cardiac failure aggravated:

Cardiac failure aggravated (1,819 drugs)

Browse all the conditions that are associated with Cardiac failure aggravated:

Cardiac failure aggravated (760 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on dofetilide (the active ingredients of Dofetilide) and Dofetilide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.