Donepezil and Post procedural haemorrhage - a phase IV clinical study of FDA data

Summary:

Post procedural haemorrhage is reported as a side effect among people who take Donepezil (donepezil hydrochloride), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Vitamin D3, and have Cataplexy.

The phase IV clinical study analyzes which people have Post procedural haemorrhage when taking Donepezil. It is created by eHealthMe based on reports of 24,262 people who have side effects when taking Donepezil from the FDA, and is updated regularly.

What is Donepezil?

Donepezil has active ingredients of donepezil hydrochloride. It is often used in dementia. eHealthMe is studying from 24,564 Donepezil users. Check the latest studies of Donepezil.

What is Post procedural haemorrhage?

Post procedural haemorrhage (post procedural bleeding) is found to be associated with 664 drugs and 854 conditions by eHealthMe. Check the latest studies of Post procedural haemorrhage.



On Jul, 09, 2026

24,262 people reported to have side effects when taking Donepezil.
Among them, 12 people (0.05%) have Post procedural haemorrhage.

Could Donepezil cause Post procedural haemorrhage?

Among these 12 people:

How long have people been on Donepezil when they have Post procedural haemorrhage? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Post procedural haemorrhage when taking Donepezil? *

  • female: 27.27 %
  • male: 72.73 %

What is the age of people who have Post procedural haemorrhage when taking Donepezil? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

What are other drugs people take besides Donepezil? *

  1. Vitamin D3: 4 people, 33.33%
  2. Myrbetriq: 3 people, 25.00%
  3. Tamsulosin: 3 people, 25.00%
  4. Metformin: 3 people, 25.00%
  5. Firdapse: 3 people, 25.00%
  6. Plavix: 3 people, 25.00%
  7. Levothyroxine Sodium: 2 people, 16.67%
  8. Omeprazole: 2 people, 16.67%
  9. Nortriptyline Hydrochloride: 2 people, 16.67%
  10. Xywav: 2 people, 16.67%

What are other side effects people have besides Post procedural haemorrhage? *

  1. Fatigue (feeling of tiredness): 3 people, 25.00%
  2. Choledocholithiasis (stones in the common bile duct): 3 people, 25.00%
  3. Weight Decreased: 3 people, 25.00%
  4. Thrombocytopenia (decrease of platelets in blood): 3 people, 25.00%
  5. Dehydration (dryness resulting from the removal of water): 3 people, 25.00%
  6. Haematocrit Abnormal: 2 people, 16.67%
  7. Fall: 2 people, 16.67%
  8. Haemoglobin Abnormal: 2 people, 16.67%
  9. Drug Ineffective: 2 people, 16.67%
  10. Head Injury: 2 people, 16.67%

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 16.67%
  2. Lambert-Eaton Syndrome (this means your immune system mistakenly targets healthy cells and tissues in the body): 2 people, 16.67%
  3. Immunodeficiency Common Variable: 2 people, 16.67%
  4. Drowsiness: 2 people, 16.67%
  5. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 16.67%
  6. Poor Quality Sleep: 1 person, 8.33%
  7. Parkinson's Disease: 1 person, 8.33%
  8. Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 1 person, 8.33%
  9. Hallucination, Visual (seeing things that aren't there): 1 person, 8.33%
  10. Cardiac Disorder: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Donepezil and have Post procedural haemorrhage?

- Check whether Post procedural haemorrhage is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Donepezil:

Post procedural haemorrhage treatments and more:

How severe was Post procedural haemorrhage and when was it recovered:

Expand to all the drugs that have ingredients of donepezil hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Donepezil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Post procedural haemorrhage:

Browse all the conditions that are associated with Post procedural haemorrhage:


How the study uses the data?

The study uses data from the FDA. It is based on donepezil hydrochloride (the active ingredients of Donepezil) and Donepezil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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