Doryx and Oesophageal ulcer - a phase IV clinical study of FDA data

Summary:

Oesophageal ulcer is reported as a side effect among people who take Doryx (doxycycline hyclate), especially for people who are female, 30-39 old, have been taking the drug for < 1 month also take Cefotan, and have Pelvic inflammatory disease.

The phase IV clinical study analyzes which people have Oesophageal ulcer when taking Doryx. It is created by eHealthMe based on reports of 696 people who have side effects when taking Doryx from the FDA, and is updated regularly.

What is Doryx?

Doryx has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 901 Doryx users. Check the latest studies of Doryx.

What is Oesophageal ulcer?

Oesophageal ulcer (ulcer of oesophagus) is found to be associated with 672 drugs and 684 conditions by eHealthMe. Check the latest studies of Oesophageal ulcer.



On Jul, 20, 2026

696 people reported to have side effects when taking Doryx.
Among them, 25 people (3.59%) have Oesophageal ulcer.

Could Doryx cause Oesophageal ulcer?

Among these 25 people:

How long have people been on Doryx when they have Oesophageal ulcer? *

  • < 1 month: 57.14 %
  • 1 - 6 months: 42.86 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Oesophageal ulcer when taking Doryx? *

  • female: 70.83 %
  • male: 29.17 %

What is the age of people who have Oesophageal ulcer when taking Doryx? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 35 %
  • 20-29: 15 %
  • 30-39: 35 %
  • 40-49: 10 %
  • 50-59: 0.0 %
  • 60+: 5 %

What are other drugs people take besides Doryx? *

  1. Claritin: 1 person, 4.00%
  2. Cefotan: 1 person, 4.00%

What are other side effects people have besides Oesophageal ulcer? *

  1. Swallowing Difficulty: 6 people, 24.00%
  2. Oesophagitis (inflammation of oesophagus): 4 people, 16.00%
  3. Weight Decreased: 3 people, 12.00%
  4. Swallowing Pain Or Burning: 3 people, 12.00%
  5. Chest Pain: 2 people, 8.00%
  6. Dyspnea (difficult or laboured breathing): 2 people, 8.00%
  7. Gastric Ulcer (stomach ulcer): 2 people, 8.00%
  8. Indigestion: 2 people, 8.00%
  9. Oesophageal Irritation: 1 person, 4.00%
  10. Oesophageal Discomfort (pain or burning feeling behind breast bone): 1 person, 4.00%

What are the existing conditions these people have? *

  1. Pelvic Inflammatory Disease: 2 people, 8.00%
  2. Upper Respiratory Tract Infection: 1 person, 4.00%
  3. Sinusitis (inflammation of sinus): 1 person, 4.00%
  4. Pharyngitis Streptococcal (inflammation of the pharynx caused by infection from. streptococcus): 1 person, 4.00%
  5. Neuroborreliosis (a disorder of the central nervous system caused by infection with a spirochete of the genus borrelia): 1 person, 4.00%
  6. Malaria (a parasitic disease due to mosquito bite): 1 person, 4.00%
  7. Chlamydial Infection (a common sexually transmitted infection (sti) in humans caused by the bacterium chlamydia trachomatis): 1 person, 4.00%
  8. Acne Cystic (skin problems that cause pimples): 1 person, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Doryx and have Oesophageal ulcer?

- Check whether Oesophageal ulcer is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Doryx:

Oesophageal ulcer treatments and more:

How severe was Oesophageal ulcer and when was it recovered:

Expand to all the drugs that have ingredients of doxycycline hyclate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Doryx:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Oesophageal ulcer:

Browse all the conditions that are associated with Oesophageal ulcer:


How the study uses the data?

The study uses data from the FDA. It is based on doxycycline hyclate (the active ingredients of Doryx) and Doryx (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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