Doxil and Anaphylactoid reaction - a phase IV clinical study of FDA data

Summary:

Anaphylactoid reaction is reported as a side effect among people who take Doxil (doxorubicin hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Aranesp, and have Anaemia of malignant disease.

The phase IV clinical study analyzes which people have Anaphylactoid reaction when taking Doxil. It is created by eHealthMe based on reports of 10,418 people who have side effects when taking Doxil from the FDA, and is updated regularly.

What is Doxil?

Doxil has active ingredients of doxorubicin hydrochloride. It is often used in ovarian cancer. eHealthMe is studying from 10,479 Doxil users. Check the latest studies of Doxil.

What is Anaphylactoid reaction?

Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation) is found to be associated with 399 drugs and 724 conditions by eHealthMe. Check the latest studies of Anaphylactoid reaction.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

10,418 people reported to have side effects when taking Doxil.
Among them, 12 people (0.12%) have Anaphylactoid reaction.

Could Doxil cause Anaphylactoid reaction?

Among these 12 people:

How long have people been on Doxil when they have Anaphylactoid reaction? *

What is the gender of people who have Anaphylactoid reaction when taking Doxil? *

female: 77.78 %
male: 22.22 %

What is the age of people who have Anaphylactoid reaction when taking Doxil? *

What are other drugs people take besides Doxil? *

What are other side effects people have besides Anaphylactoid reaction? *

Hypotension (abnormally low blood pressure): 3 people, 25.00%
Infusion Related Reaction: 2 people, 16.67%
Back Pain: 2 people, 16.67%
Chest Pain: 2 people, 16.67%
Fainting (loss of consciousness and postural tone): 2 people, 16.67%
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 1 person, 8.33%
Dizziness: 1 person, 8.33%
Dyspnea (difficult or laboured breathing): 1 person, 8.33%
High Blood Pressure: 1 person, 8.33%
Urticaria (rash of round, red welts on the skin that itch intensely): 1 person, 8.33%

What are the existing conditions these people have? *

Sarcoma (rare cancers that develop in the muscle, bone, nerves, cartilage, tendons, blood vessels and the fatty and fibrous tissues): 1 person, 8.33%
Hepatic Neoplasm Malignant (liver cancer): 1 person, 8.33%
Breast Cancer: 1 person, 8.33%
Anaemia Of Malignant Disease: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Doxil and have Anaphylactoid reaction?

- Check whether Anaphylactoid reaction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Doxil:

Doxil (10,479 reports)

Browse all side effects of Doxil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Anaphylactoid reaction:

Anaphylactoid reaction (399 drugs)

Browse all the conditions that are associated with Anaphylactoid reaction:

Anaphylactoid reaction (724 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on doxorubicin hydrochloride (the active ingredients of Doxil) and Doxil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.