Doxil and Faecal incontinence - a phase IV clinical study of FDA data
Summary:
Faecal incontinence is reported as a side effect among people who take Doxil (doxorubicin hydrochloride), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Gabapentin, and have Metastases to bone.
The phase IV clinical study analyzes which people have Faecal incontinence when taking Doxil. It is created by eHealthMe based on reports of 10,418 people who have side effects when taking Doxil from the FDA, and is updated regularly.
What is Doxil?
Doxil has active ingredients of doxorubicin hydrochloride. It is often used in ovarian cancer. eHealthMe is studying from 10,479 Doxil users. Check the latest studies of Doxil.
What is Faecal incontinence?
Faecal incontinence (a lack of control over passing stool) is found to be associated with 759 drugs and 1,384 conditions by eHealthMe. Check the latest studies of Faecal incontinence.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
10,418 people reported to have side effects when taking Doxil.
Among them, 22 people (0.21%) have Faecal incontinence.

Among these 22 people:
How long have people been on Doxil when they have Faecal incontinence? *
- < 1 month: 17.65 %
- 1 - 6 months: 82.35 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Faecal incontinence when taking Doxil? *
- female: 27.78 %
- male: 72.22 %
What is the age of people who have Faecal incontinence when taking Doxil? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 17.65 %
- 50-59: 0.0 %
- 60+: 82.35 %
What are other drugs people take besides Doxil? *
- Zometa: 15 people, 68.18%
- Ondansetron: 15 people, 68.18%
- Gabapentin: 15 people, 68.18%
- Eptifibatide: 14 people, 63.64%
- Pantoprazole: 14 people, 63.64%
- Protamine Sulfate: 14 people, 63.64%
- Ativan: 14 people, 63.64%
- Prilosec: 14 people, 63.64%
- Cytoxan: 14 people, 63.64%
- Clopidogrel Bisulfate: 14 people, 63.64%
What are other side effects people have besides Faecal incontinence? *
- Urinary Incontinence (inability to control the flow of urine and involuntary urination): 17 people, 77.27%
- Thrombocytopenia (decrease of platelets in blood): 17 people, 77.27%
- Weakness: 16 people, 72.73%
- Weight Decreased: 15 people, 68.18%
- Pain In Jaw: 15 people, 68.18%
- Neuropathy Peripheral (surface nerve damage): 15 people, 68.18%
- Anaemia (lack of blood): 15 people, 68.18%
- Periodontal Disease (disease that attacks the gum and bone and around the teeth): 15 people, 68.18%
- Swallowing Difficulty: 15 people, 68.18%
- Pain: 15 people, 68.18%
What are the existing conditions these people have? *
- Multiple Myeloma (cancer of the plasma cells): 15 people, 68.18%
- Metastases To Bone (cancer spreads to bone): 15 people, 68.18%
- Stress And Anxiety: 14 people, 63.64%
- Pain: 14 people, 63.64%
- High Blood Pressure: 14 people, 63.64%
- Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough): 14 people, 63.64%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 14 people, 63.64%
- Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 14 people, 63.64%
- Insomnia (sleeplessness): 9 people, 40.91%
- Cancer - Throat Or Larynx: 3 people, 13.64%
* Approximation only. Some reports may have incomplete information.
Do you take Doxil and have Faecal incontinence?
- Check whether Faecal incontinence is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Doxil:
- Doxil (10,479 reports)
Faecal incontinence treatments and more:
- Faecal incontinence (8,187 reports)
How severe was Faecal incontinence and when was it recovered:
Expand to all the drugs that have ingredients of doxorubicin hydrochloride:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Doxil:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Faecal incontinence:
- Faecal incontinence (759 drugs)
Browse all the conditions that are associated with Faecal incontinence:
- Faecal incontinence (1,384 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on doxorubicin hydrochloride (the active ingredients of Doxil) and Doxil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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