Doxil and Hypothyroidism - a phase IV clinical study of FDA data
Summary:
Hypothyroidism is reported as a side effect among people who take Doxil (doxorubicin hydrochloride), especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months also take Zometa, and have Agranulocytosis.
The phase IV clinical study analyzes which people have Hypothyroidism when taking Doxil. It is created by eHealthMe based on reports of 10,418 people who have side effects when taking Doxil from the FDA, and is updated regularly.
What is Doxil?
Doxil has active ingredients of doxorubicin hydrochloride. It is often used in ovarian cancer. eHealthMe is studying from 10,479 Doxil users. Check the latest studies of Doxil.
What is Hypothyroidism?
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development) is found to be associated with 1,616 drugs and 2,599 conditions by eHealthMe. Check the latest studies of Hypothyroidism.
10,418 people reported to have side effects when taking Doxil.
Among them, 12 people (0.12%) have Hypothyroidism.

Among these 12 people:
How long have people been on Doxil when they have Hypothyroidism? *
- < 1 month: 20 %
- 1 - 6 months: 80 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Hypothyroidism when taking Doxil? *
- female: 58.33 %
- male: 41.67 %
What is the age of people who have Hypothyroidism when taking Doxil? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 8.33 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 66.67 %
- 50-59: 8.33 %
- 60+: 16.67 %
What are other drugs people take besides Doxil? *
- Zometa: 7 people, 58.33%
- Ibuprofen: 6 people, 50.00%
- Ativan: 5 people, 41.67%
- Taxol: 5 people, 41.67%
- Cytoxan: 5 people, 41.67%
- Navelbine: 5 people, 41.67%
- Carboplatin: 4 people, 33.33%
- Chantix: 4 people, 33.33%
- Naproxen: 4 people, 33.33%
- Movicol: 4 people, 33.33%
What are other side effects people have besides Hypothyroidism? *
- Fever: 10 people, 83.33%
- Pain: 10 people, 83.33%
- Nausea And Vomiting: 10 people, 83.33%
- Joint Pain: 10 people, 83.33%
- Fatigue (feeling of tiredness): 10 people, 83.33%
- Nausea (feeling of having an urge to vomit): 9 people, 75.00%
- Dyspnea (difficult or laboured breathing): 9 people, 75.00%
- Sleep Disorder: 8 people, 66.67%
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 7 people, 58.33%
- Cough: 7 people, 58.33%
What are the existing conditions these people have? *
- Pneumonia: 4 people, 33.33%
- Pain In Extremity: 4 people, 33.33%
- Pain: 4 people, 33.33%
- Hodgkin's Lymphoma (cancer originating from white blood cells): 4 people, 33.33%
- High Blood Pressure: 4 people, 33.33%
- Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 4 people, 33.33%
- Back Pain: 4 people, 33.33%
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 4 people, 33.33%
- Multiple Myeloma (cancer of the plasma cells): 2 people, 16.67%
- Neoplasm Malignant (cancer tumour): 1 person, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Doxil and have Hypothyroidism?
- Check whether Hypothyroidism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Doxil:
- Doxil (10,479 reports)
Hypothyroidism treatments and more:
- Hypothyroidism (168,065 reports)
How severe was Hypothyroidism and when was it recovered:
Expand to all the drugs that have ingredients of doxorubicin hydrochloride:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Doxil:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Hypothyroidism:
- Hypothyroidism (1,616 drugs)
Browse all the conditions that are associated with Hypothyroidism:
- Hypothyroidism (2,599 conditions)
Related publications that referenced our studies
- Ezeji GC, Inoue T, Bahtiyar G, Sacerdote A, "Hallucinations associated with miglitol use in a patient with chronic kidney disease and hypothyroidism", BMJ case reports, 2015 Feb .
- Ezeji GC, Inoue T, Bahtiyar G, Sacerdote A, "Hallucinations associated with miglitol use in a patient with chronic kidney disease and hypothyroidism", BMJ case reports, 2015 Feb .
How the study uses the data?
The study uses data from the FDA. It is based on doxorubicin hydrochloride (the active ingredients of Doxil) and Doxil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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