Doxorubicin hydrochloride and Systemic sclerosis (scleroderma) - a phase IV clinical study of FDA data

Summary:

Systemic sclerosis (scleroderma) is reported as a side effect among people who take Doxorubicin hydrochloride (doxorubicin hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Cellcept, and have Diffuse large b-cell lymphoma recurrent.

The phase IV clinical study analyzes which people have Systemic sclerosis (scleroderma) when taking Doxorubicin hydrochloride. It is created by eHealthMe based on reports of 25,305 people who have side effects when taking Doxorubicin hydrochloride from the FDA, and is updated regularly.

What is Doxorubicin hydrochloride?

Doxorubicin hydrochloride has active ingredients of doxorubicin hydrochloride. eHealthMe is studying from 25,343 Doxorubicin hydrochloride users. Check the latest studies of Doxorubicin hydrochloride.

What is Systemic sclerosis (scleroderma)?

Systemic sclerosis (scleroderma) (an autoimmune or connective tissue disease. it is characterized by thickening of the skin) is found to be associated with 493 drugs and 857 conditions by eHealthMe. Check the latest studies of Systemic sclerosis (scleroderma).

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 17, 2026

25,305 people reported to have side effects when taking Doxorubicin hydrochloride.
Among them, 12 people (0.05%) have Systemic sclerosis (scleroderma).

Could Doxorubicin hydrochloride cause Systemic sclerosis (scleroderma)?

Among these 12 people:

How long have people been on Doxorubicin hydrochloride when they have Systemic sclerosis (scleroderma)? *

What is the gender of people who have Systemic sclerosis (scleroderma) when taking Doxorubicin hydrochloride? *

female: 41.67 %
male: 58.33 %

What is the age of people who have Systemic sclerosis (scleroderma) when taking Doxorubicin hydrochloride? *

What are other drugs people take besides Doxorubicin hydrochloride? *

What are other side effects people have besides Systemic sclerosis (scleroderma)? *

Rashes (redness): 4 people, 33.33%
Total Lung Capacity Decreased: 3 people, 25.00%
Pain: 3 people, 25.00%
Musculoskeletal Disorder (disease of the body's muscles, joints, tendons, ligaments and nerves): 3 people, 25.00%
Morphea: 3 people, 25.00%
Malignant Neoplasm Progression (cancer tumour came back): 3 people, 25.00%
Drug Ineffective: 3 people, 25.00%
Diffuse Large B-Cell Lymphoma Recurrent (recurrent cancer of b cells, a type of white blood cell): 3 people, 25.00%
Swelling: 2 people, 16.67%
Superinfection: 2 people, 16.67%

What are the existing conditions these people have? *

Testicular Neoplasm (testes tumour): 3 people, 25.00%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 3 people, 25.00%
Diffuse Large B-Cell Lymphoma Recurrent (recurrent cancer of b cells, a type of white blood cell): 3 people, 25.00%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 16.67%
Chronic Graft Versus Host Disease (immune cells attack the host's body cells after transplant): 2 people, 16.67%
Rashes (redness): 1 person, 8.33%
Hodgkin's Lymphoma (cancer originating from white blood cells): 1 person, 8.33%
Breast Cancer Metastatic: 1 person, 8.33%
Breast Cancer: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Doxorubicin hydrochloride and have Systemic sclerosis (scleroderma)?

- Check whether Systemic sclerosis (scleroderma) is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Doxorubicin hydrochloride:

Doxorubicin hydrochloride (25,343 reports)

Browse all side effects of Doxorubicin hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Systemic sclerosis (scleroderma):

Systemic sclerosis (scleroderma) (493 drugs)

Browse all the conditions that are associated with Systemic sclerosis (scleroderma):

Systemic sclerosis (scleroderma) (857 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on doxorubicin hydrochloride (the active ingredients of Doxorubicin hydrochloride) and Doxorubicin hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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