Doxycycline hyclate and Disease progression - a phase IV clinical study of FDA data

Summary:

Disease progression is reported as a side effect among people who take Doxycycline hyclate (doxycycline hyclate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Imbruvica, and have Pain.

The phase IV clinical study analyzes which people have Disease progression when taking Doxycycline hyclate. It is created by eHealthMe based on reports of 16,516 people who have side effects when taking Doxycycline hyclate from the FDA, and is updated regularly.

What is Doxycycline hyclate?

Doxycycline hyclate has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 17,884 Doxycycline hyclate users. Check the latest studies of Doxycycline hyclate.

What is Disease progression?

Disease progression is found to be associated with 1,797 drugs and 2,257 conditions by eHealthMe. Check the latest studies of Disease progression.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

16,516 people reported to have side effects when taking Doxycycline hyclate.
Among them, 74 people (0.45%) have Disease progression.

Could Doxycycline hyclate cause Disease progression?

Among these 74 people:

How long have people been on Doxycycline hyclate when they have Disease progression? *

What is the gender of people who have Disease progression when taking Doxycycline hyclate? *

female: 64.41 %
male: 35.59 %

What is the age of people who have Disease progression when taking Doxycycline hyclate? *

What are other drugs people take besides Doxycycline hyclate? *

What are other side effects people have besides Disease progression? *

Fatigue (feeling of tiredness): 15 people, 20.27%
Thrombocytopenia (decrease of platelets in blood): 14 people, 18.92%
Joint Pain: 11 people, 14.86%
Anaemia (lack of blood): 10 people, 13.51%
Drug Ineffective: 10 people, 13.51%
Dyspnea (difficult or laboured breathing): 9 people, 12.16%
Increased Tendency To Bruise (increased tendency to injure the underlying soft tissue or bone): 8 people, 10.81%
Pain In Extremity: 8 people, 10.81%
Fever: 7 people, 9.46%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 9.46%

What are the existing conditions these people have? *

Pain: 8 people, 10.81%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 7 people, 9.46%
Primary Myelofibrosis (primary disorder of the bone marrow): 6 people, 8.11%
Lung Neoplasm Malignant (cancer tumour of lung): 5 people, 6.76%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 5.41%
Colon Cancer: 4 people, 5.41%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 4 people, 5.41%
Renal Cell Carcinoma (a kidney cancer): 3 people, 4.05%
Raynaud's Phenomenon (discoloration of the fingers, toes, and occasionally other areas): 3 people, 4.05%
Breast Cancer: 3 people, 4.05%

* Approximation only. Some reports may have incomplete information.

Do you take Doxycycline hyclate and have Disease progression?

- Check whether Disease progression is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Doxycycline hyclate:

Doxycycline hyclate (17,884 reports)

Browse all side effects of Doxycycline hyclate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Disease progression:

Disease progression (1,797 drugs)

Browse all the conditions that are associated with Disease progression:

Disease progression (2,257 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on doxycycline hyclate (the active ingredients of Doxycycline hyclate) and Doxycycline hyclate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.