Doxycycline hyclate and Injection site mass - a phase IV clinical study of FDA data

Summary:

Injection site mass is reported as a side effect among people who take Doxycycline hyclate (doxycycline hyclate), especially for people who are female, 60+ old, also take Epinephrine, and have Immunodeficiency common variable.

The phase IV clinical study analyzes which people have Injection site mass when taking Doxycycline hyclate. It is created by eHealthMe based on reports of 16,516 people who have side effects when taking Doxycycline hyclate from the FDA, and is updated regularly.

What is Doxycycline hyclate?

Doxycycline hyclate has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 17,884 Doxycycline hyclate users. Check the latest studies of Doxycycline hyclate.

What is Injection site mass?

Injection site mass is found to be associated with 832 drugs and 787 conditions by eHealthMe. Check the latest studies of Injection site mass.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

16,516 people reported to have side effects when taking Doxycycline hyclate.
Among them, 28 people (0.17%) have Injection site mass.

Could Doxycycline hyclate cause Injection site mass?

Among these 28 people:

What is the gender of people who have Injection site mass when taking Doxycycline hyclate? *

  • female: 55.56 %
  • male: 44.44 %

What is the age of people who have Injection site mass when taking Doxycycline hyclate? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 13.64 %
  • 40-49: 0.0 %
  • 50-59: 31.82 %
  • 60+: 54.55 %

What are other drugs people take besides Doxycycline hyclate? *

  1. Acetaminophen: 15 people, 53.57%
  2. Epinephrine: 15 people, 53.57%
  3. Sodium Chloride: 11 people, 39.29%
  4. Pantoprazole Sodium: 11 people, 39.29%
  5. Melatonin: 11 people, 39.29%
  6. Omeprazole: 10 people, 35.71%
  7. Lidocaine: 10 people, 35.71%
  8. Prednisone: 9 people, 32.14%
  9. Aspirin: 8 people, 28.57%
  10. Proair Hfa: 7 people, 25.00%

What are other side effects people have besides Injection site mass? *

  1. Rashes (redness): 8 people, 28.57%
  2. Eye Pruritus (eye itching): 6 people, 21.43%
  3. Urinary Tract Infection: 6 people, 21.43%
  4. Dermal Cyst: 6 people, 21.43%
  5. Cellulitis (infection under the skin): 6 people, 21.43%
  6. Fever: 6 people, 21.43%
  7. Paranasal Sinus Discomfort: 6 people, 21.43%
  8. Nosebleed (bleeding from nose): 5 people, 17.86%
  9. Pain In Extremity: 5 people, 17.86%
  10. Pain: 5 people, 17.86%

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 9 people, 32.14%
  2. Immune System Disorder: 6 people, 21.43%
  3. Hypergammaglobulinaemia (elevated levels of gamma globulin): 3 people, 10.71%
  4. High Blood Cholesterol: 3 people, 10.71%
  5. Psoriasis (immune-mediated disease that affects the skin): 2 people, 7.14%
  6. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 7.14%
  7. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 7.14%
  8. Infertility Female: 1 person, 3.57%
  9. Idiopathic Thrombocytopenic Purpura (Itp) (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 1 person, 3.57%
  10. Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 1 person, 3.57%

* Approximation only. Some reports may have incomplete information.

Do you take Doxycycline hyclate and have Injection site mass?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Doxycycline hyclate:

Injection site mass treatments and more:

How severe was Injection site mass and when was it recovered:

Expand to all the drugs that have ingredients of doxycycline hyclate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Doxycycline hyclate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Injection site mass:

Browse all the conditions that are associated with Injection site mass:


How the study uses the data?

The study uses data from the FDA. It is based on doxycycline hyclate (the active ingredients of Doxycycline hyclate) and Doxycycline hyclate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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