Doxycycline hyclate and Transaminases increased - a phase IV clinical study of FDA data

Summary:

Transaminases increased is reported as a side effect among people who take Doxycycline hyclate (doxycycline hyclate), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Cubicin, and have Osteomyelitis.

The phase IV clinical study analyzes which people have Transaminases increased when taking Doxycycline hyclate. It is created by eHealthMe based on reports of 16,516 people who have side effects when taking Doxycycline hyclate from the FDA, and is updated regularly.

What is Doxycycline hyclate?

Doxycycline hyclate has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 17,884 Doxycycline hyclate users. Check the latest studies of Doxycycline hyclate.

What is Transaminases increased?

Transaminases increased is found to be associated with 1,162 drugs and 1,514 conditions by eHealthMe. Check the latest studies of Transaminases increased.

On Jul, 07, 2026

16,516 people reported to have side effects when taking Doxycycline hyclate.
Among them, 30 people (0.18%) have Transaminases increased.

Could Doxycycline hyclate cause Transaminases increased?

Among these 30 people:

How long have people been on Doxycycline hyclate when they have Transaminases increased? *

What is the gender of people who have Transaminases increased when taking Doxycycline hyclate? *

female: 20.69 %
male: 79.31 %

What is the age of people who have Transaminases increased when taking Doxycycline hyclate? *

What are other drugs people take besides Doxycycline hyclate? *

What are other side effects people have besides Transaminases increased? *

Thrombocytopenia (decrease of platelets in blood): 12 people, 40.00%
General Physical Health Deterioration (weak health status): 12 people, 40.00%
Staphylococcal Infection (an infection with staphylococcus bacteria): 11 people, 36.67%
Hypophagia (reduced food intake): 11 people, 36.67%
Rashes (redness): 10 people, 33.33%
Fatigue (feeling of tiredness): 8 people, 26.67%
Fever: 8 people, 26.67%
Dizziness: 8 people, 26.67%
Chronic Thyroiditis (long lasting inflammation of thyroid gland): 7 people, 23.33%
Rash Maculo-Papular (red area on the skin that is covered with small confluent bumps): 7 people, 23.33%

What are the existing conditions these people have? *

Paraspinal Abscess: 11 people, 36.67%
Intervertebral Discitis (infection in the intervertebral disc space): 11 people, 36.67%
Osteomyelitis (infection of bone): 11 people, 36.67%
Malignant Melanoma (skin cancer rises from melancytes): 7 people, 23.33%
Sepsis (a severe blood infection that can lead to organ failure and death): 5 people, 16.67%
Burkholderia Cepacia Complex Infection (complex infection by group of bacteria burkholderia cepacia -resistant to common antibiotics): 5 people, 16.67%
Tenosynovitis (inflammation of the fluid-filled sheath (called the synovium) that surrounds a tendon): 2 people, 6.67%
Ovulation Induction: 1 person, 3.33%
Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 1 person, 3.33%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 1 person, 3.33%

* Approximation only. Some reports may have incomplete information.

Do you take Doxycycline hyclate and have Transaminases increased?

- Check whether Transaminases increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Doxycycline hyclate:

Doxycycline hyclate (17,884 reports)

Browse all side effects of Doxycycline hyclate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Transaminases increased:

Transaminases increased (1,162 drugs)

Browse all the conditions that are associated with Transaminases increased:

Transaminases increased (1,514 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on doxycycline hyclate (the active ingredients of Doxycycline hyclate) and Doxycycline hyclate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.