Doxycycline and Chondropathy - a phase IV clinical study of FDA data

Summary:

Chondropathy is reported as a side effect among people who take Doxycycline (doxycycline hyclate), especially for people who are female, 50-59 old, also take Oxycodone, and have Hiv infection.

The phase IV clinical study analyzes which people have Chondropathy when taking Doxycycline. It is created by eHealthMe based on reports of 57,458 people who have side effects when taking Doxycycline from the FDA, and is updated regularly.

What is Doxycycline?

Doxycycline has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 60,868 Doxycycline users. Check the latest studies of Doxycycline.

What is Chondropathy?

Chondropathy (disease of the cartilage) is found to be associated with 365 drugs and 434 conditions by eHealthMe. Check the latest studies of Chondropathy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

57,458 people reported to have side effects when taking Doxycycline.
Among them, 12 people (0.02%) have Chondropathy.

Among these 12 people:

What is the gender of people who have Chondropathy when taking Doxycycline? *

female: 58.33 %
male: 41.67 %

What is the age of people who have Chondropathy when taking Doxycycline? *

What are other drugs people take besides Doxycycline? *

Oxycodone: 6 people, 50.00%
Alphagan P: 5 people, 41.67%
Advair Hfa: 5 people, 41.67%
Sulfamethoxazole And Trimethoprim: 4 people, 33.33%
Sertraline: 4 people, 33.33%
Seroquel: 4 people, 33.33%
Avelox: 4 people, 33.33%
Proair Hfa: 4 people, 33.33%
Cialis: 4 people, 33.33%
Oxycodone And Acetaminophen: 4 people, 33.33%

What are other side effects people have besides Chondropathy? *

Pain: 7 people, 58.33%
Gait Disturbance: 6 people, 50.00%
Stress And Anxiety: 6 people, 50.00%
Anhedonia (inability to experience pleasure from activities usually found enjoyable): 5 people, 41.67%
Osteoporosis (bones weak and more likely to break): 5 people, 41.67%
Bone Density Abnormal: 4 people, 33.33%
Emotional Distress: 4 people, 33.33%
Tooth Loss: 4 people, 33.33%
Muscle Atrophy (a decrease in the mass of the muscle): 4 people, 33.33%
Aseptic Necrosis (the death of bone tissue due to a lack of blood supply): 4 people, 33.33%

What are the existing conditions these people have? *

Hiv Infection: 4 people, 33.33%
Staphylococcus Test Positive: 1 person, 8.33%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 8.33%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 8.33%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 8.33%
Multiple Myeloma (cancer of the plasma cells): 1 person, 8.33%
Lyme Disease (a bacterial infection that is spread to humans by infected ticks): 1 person, 8.33%
Irritable Bowel Syndrome: 1 person, 8.33%
Drowsiness: 1 person, 8.33%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Doxycycline and have Chondropathy?

- Check whether Chondropathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Doxycycline:

Doxycycline (60,868 reports)

Chondropathy treatments and more:

Chondropathy (3,939 reports)

Browse all side effects of Doxycycline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Chondropathy:

Chondropathy (365 drugs)

Browse all the conditions that are associated with Chondropathy:

Chondropathy (434 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on doxycycline hyclate (the active ingredients of Doxycycline) and Doxycycline (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.