Doxycycline and Eyelids pruritus - a phase IV clinical study of FDA data

Summary:

Eyelids pruritus is reported as a side effect among people who take Doxycycline (doxycycline hyclate), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Tarceva, and have Dermatitis atopic.

The phase IV clinical study analyzes which people have Eyelids pruritus when taking Doxycycline. It is created by eHealthMe based on reports of 57,458 people who have side effects when taking Doxycycline from the FDA, and is updated regularly.

What is Doxycycline?

Doxycycline has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 60,868 Doxycycline users. Check the latest studies of Doxycycline.

What is Eyelids pruritus?

Eyelids pruritus (eyelids itching) is found to be associated with 165 drugs and 322 conditions by eHealthMe. Check the latest studies of Eyelids pruritus.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

57,458 people reported to have side effects when taking Doxycycline.
Among them, 12 people (0.02%) have Eyelids pruritus.

Could Doxycycline cause Eyelids pruritus?

Among these 12 people:

How long have people been on Doxycycline when they have Eyelids pruritus? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Eyelids pruritus when taking Doxycycline? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Eyelids pruritus when taking Doxycycline? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 9.09 %
  • 30-39: 0.0 %
  • 40-49: 27.27 %
  • 50-59: 36.36 %
  • 60+: 27.27 %

What are other drugs people take besides Doxycycline? *

  1. Tarceva: 4 people, 33.33%
  2. Zyrtec: 3 people, 25.00%
  3. Niaspan: 3 people, 25.00%
  4. Dupixent: 3 people, 25.00%
  5. Paxil: 3 people, 25.00%
  6. Pepcid: 3 people, 25.00%
  7. Zoloft: 3 people, 25.00%
  8. Proair Hfa: 3 people, 25.00%
  9. Lyrica: 3 people, 25.00%
  10. Simponi: 3 people, 25.00%

What are other side effects people have besides Eyelids pruritus? *

  1. Rashes (redness): 7 people, 58.33%
  2. Vision Blurred: 6 people, 50.00%
  3. Itching: 6 people, 50.00%
  4. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 4 people, 33.33%
  5. Eye Irritation: 4 people, 33.33%
  6. Skin Exfoliation (removal of the oldest dead skin cells): 4 people, 33.33%
  7. Eye Pruritus (eye itching): 4 people, 33.33%
  8. Lip Dry: 4 people, 33.33%
  9. Nail Bed Inflammation (infection of nail bed): 3 people, 25.00%
  10. Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 3 people, 25.00%

What are the existing conditions these people have? *

  1. Lung Neoplasm Malignant (cancer tumour of lung): 4 people, 33.33%
  2. Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 4 people, 33.33%
  3. Lyme Disease (a bacterial infection that is spread to humans by infected ticks): 3 people, 25.00%
  4. Asthma: 2 people, 16.67%
  5. Nausea And Vomiting: 1 person, 8.33%
  6. Nausea (feeling of having an urge to vomit): 1 person, 8.33%
  7. Bronchial Carcinoma (lung cancer): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Doxycycline and have Eyelids pruritus?

- Check whether Eyelids pruritus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Doxycycline:

Eyelids pruritus treatments and more:

How severe was Eyelids pruritus and when was it recovered:

Expand to all the drugs that have ingredients of doxycycline hyclate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Doxycycline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Eyelids pruritus:

Browse all the conditions that are associated with Eyelids pruritus:


How the study uses the data?

The study uses data from the FDA. It is based on doxycycline hyclate (the active ingredients of Doxycycline) and Doxycycline (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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