Doxycycline and Ventricular arrhythmia - a phase IV clinical study of FDA data

Summary:

Ventricular arrhythmia is reported as a side effect among people who take Doxycycline (doxycycline hyclate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Entresto, and have Localised infection.

The phase IV clinical study analyzes which people have Ventricular arrhythmia when taking Doxycycline. It is created by eHealthMe based on reports of 57,458 people who have side effects when taking Doxycycline from the FDA, and is updated regularly.

What is Doxycycline?

Doxycycline has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 60,868 Doxycycline users. Check the latest studies of Doxycycline.

What is Ventricular arrhythmia?

Ventricular arrhythmia (problem with the rate or rhythm of the heartbeat) is found to be associated with 468 drugs and 559 conditions by eHealthMe. Check the latest studies of Ventricular arrhythmia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

57,458 people reported to have side effects when taking Doxycycline.
Among them, 22 people (0.04%) have Ventricular arrhythmia.

Could Doxycycline cause Ventricular arrhythmia?

Among these 22 people:

How long have people been on Doxycycline when they have Ventricular arrhythmia? *

What is the gender of people who have Ventricular arrhythmia when taking Doxycycline? *

female: 54.55 %
male: 45.45 %

What is the age of people who have Ventricular arrhythmia when taking Doxycycline? *

What are other drugs people take besides Doxycycline? *

What are other side effects people have besides Ventricular arrhythmia? *

Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 12 people, 54.55%
Nausea (feeling of having an urge to vomit): 10 people, 45.45%
Electrocardiogram Qrs Complex Prolonged: 10 people, 45.45%
Abdominal Pain: 8 people, 36.36%
Constipation: 7 people, 31.82%
Orthopnea (shortness of breath (dyspnea) when lying down): 7 people, 31.82%
Abdominal Distension: 7 people, 31.82%
Dyspnea (difficult or laboured breathing): 7 people, 31.82%
Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 5 people, 22.73%
Fainting (loss of consciousness and postural tone): 4 people, 18.18%

What are the existing conditions these people have? *

Localised Infection (infection at the single location): 10 people, 45.45%
Cardiac Failure: 3 people, 13.64%
Wheezing (a high-pitched whistling sound made while you breath): 2 people, 9.09%
Multiple Myeloma (cancer of the plasma cells): 2 people, 9.09%
Blood Glucose Increased: 2 people, 9.09%
Malaria (a parasitic disease due to mosquito bite): 1 person, 4.55%
High Blood Pressure: 1 person, 4.55%
Cardiac Failure Congestive: 1 person, 4.55%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Doxycycline and have Ventricular arrhythmia?

- Check whether Ventricular arrhythmia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Doxycycline:

Doxycycline (60,868 reports)

Browse all side effects of Doxycycline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ventricular arrhythmia:

Ventricular arrhythmia (468 drugs)

Browse all the conditions that are associated with Ventricular arrhythmia:

Ventricular arrhythmia (559 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on doxycycline hyclate (the active ingredients of Doxycycline) and Doxycycline (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.