Droxidopa and Constipation - a phase IV clinical study of FDA data

Summary:

Constipation is reported as a side effect among people who take Droxidopa (droxidopa), especially for people who are female, 60+ old, also take Nuplazid, and have Parkinson's disease.

The phase IV clinical study analyzes which people have Constipation when taking Droxidopa. It is created by eHealthMe based on reports of 1,093 people who have side effects when taking Droxidopa from the FDA, and is updated regularly.

What is Droxidopa?

Droxidopa has active ingredients of droxidopa. eHealthMe is studying from 1,093 Droxidopa users. Check the latest studies of Droxidopa.

What is Constipation?

Constipation is found to be associated with 3,003 drugs and 4,605 conditions by eHealthMe. Check the latest studies of Constipation.

On Jun, 20, 2026

1,093 people reported to have side effects when taking Droxidopa.
Among them, 28 people (2.56%) have Constipation.

Among these 28 people:

What is the gender of people who have Constipation when taking Droxidopa? *

female: 52 %
male: 48 %

What is the age of people who have Constipation when taking Droxidopa? *

What are other drugs people take besides Droxidopa? *

Nuplazid: 6 people, 21.43%
Zonisamide: 5 people, 17.86%
Entacapone: 4 people, 14.29%
Donepezil Hydrochloride: 4 people, 14.29%
Nitrofurantoin: 3 people, 10.71%
Lexapro: 3 people, 10.71%
Ongentys: 3 people, 10.71%
Estradiol: 3 people, 10.71%
Rivastigmine: 3 people, 10.71%
Rytary: 3 people, 10.71%

What are other side effects people have besides Constipation? *

Nausea (feeling of having an urge to vomit): 6 people, 21.43%
Hallucinations (sensations that appear real but are created by your mind): 5 people, 17.86%
Anaemia (lack of blood): 5 people, 17.86%
Malaise (a feeling of general discomfort or uneasiness): 5 people, 17.86%
Fall: 5 people, 17.86%
Dyspnea (difficult or laboured breathing): 5 people, 17.86%
Dehydration (dryness resulting from the removal of water): 5 people, 17.86%
Drooling (drop saliva uncontrollably from the mouth): 4 people, 14.29%
Insomnia (sleeplessness): 4 people, 14.29%
Gastric Ulcer Haemorrhage (bleeding ulcer of stomach): 4 people, 14.29%

What are the existing conditions these people have? *

Parkinson's Disease: 19 people, 67.86%
Hallucinations (sensations that appear real but are created by your mind): 5 people, 17.86%
Delusion (a false belief or opinion): 4 people, 14.29%
Osteoporosis (bones weak and more likely to break): 4 people, 14.29%
Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 4 people, 14.29%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 4 people, 14.29%
Hepatic Steatosis (fatty liver disease): 3 people, 10.71%
Neuroleptic Malignant Syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents): 3 people, 10.71%
Tremor (trembling or shaking movements in one or more parts of your body): 3 people, 10.71%
Insomnia (sleeplessness): 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Droxidopa and have Constipation?

- Check whether Constipation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Droxidopa:

Droxidopa (1,093 reports)

Constipation treatments and more:

Constipation (337,878 reports)

Browse all side effects of Droxidopa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Constipation:

Constipation (3,003 drugs)

Browse all the conditions that are associated with Constipation:

Constipation (4,605 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on droxidopa (the active ingredients of Droxidopa) and Droxidopa (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.