Duac and Itching - a phase IV clinical study of FDA data

Summary:

Itching is reported as a side effect among people who take Duac (benzoyl peroxide; clindamycin phosphate), especially for people who are female, 10-19 old, have been taking the drug for < 1 month also take Lisinopril, and have Narcolepsy.

The phase IV clinical study analyzes which people have Itching when taking Duac. It is created by eHealthMe based on reports of 718 people who have side effects when taking Duac from the FDA, and is updated regularly.

What is Duac?

Duac has active ingredients of benzoyl peroxide; clindamycin phosphate. It is often used in acne. eHealthMe is studying from 745 Duac users. Check the latest studies of Duac.

What is Itching?

Itching is found to be associated with 3,211 drugs and 4,538 conditions by eHealthMe. Check the latest studies of Itching.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

718 people reported to have side effects when taking Duac.
Among them, 64 people (8.91%) have Itching.

Among these 64 people:

How long have people been on Duac when they have Itching? *

What is the gender of people who have Itching when taking Duac? *

female: 83.61 %
male: 16.39 %

What is the age of people who have Itching when taking Duac? *

What are other drugs people take besides Duac? *

What are other side effects people have besides Itching? *

Rashes (redness): 37 people, 57.81%
Swelling Face: 15 people, 23.44%
Urticaria (rash of round, red welts on the skin that itch intensely): 10 people, 15.62%
Dry Skin: 9 people, 14.06%
Dermatitis Contact (skin reaction (dermatitis) resulting from exposure to allergens): 7 people, 10.94%
Swelling: 7 people, 10.94%
Skin Exfoliation (removal of the oldest dead skin cells): 6 people, 9.38%
Oedema (fluid collection in tissue): 6 people, 9.38%
Skin Irritation: 6 people, 9.38%
Rash Macular (small, flat red spots): 5 people, 7.81%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 4.69%
Skin Hyperpigmentation (disorders affect the colour of your skin): 2 people, 3.12%
Rash Pustular (redness with pustules): 2 people, 3.12%
Urticaria (rash of round, red welts on the skin that itch intensely): 1 person, 1.56%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 1.56%
Arthritis Reactive (autoimmune condition that develops in response to an infection in another part of the body): 1 person, 1.56%
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 1 person, 1.56%
Chest Pain: 1 person, 1.56%
Cough: 1 person, 1.56%
Diarrhea: 1 person, 1.56%

* Approximation only. Some reports may have incomplete information.

Do you take Duac and have Itching?

- Check whether Itching is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Duac:

Duac (745 reports)

Itching treatments and more:

Itching (398,823 reports)

How severe was Itching and when was it recovered:

Itching in Duac

Expand to all the drugs that have ingredients of benzoyl peroxide; clindamycin phosphate:

Itching and drugs with ingredients of benzoyl peroxide; clindamycin phosphate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Duac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Itching:

Itching (3,211 drugs)

Browse all the conditions that are associated with Itching:

Itching (4,538 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on benzoyl peroxide; clindamycin phosphate (the active ingredients of Duac) and Duac (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.