Duavee and Headache - a phase IV clinical study of FDA data

Summary:

Headache is reported as a side effect among people who take Duavee (conjugated estrogens; bazedoxifene), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Albuterol Sulfate, and have Hot flush.

The phase IV clinical study analyzes which people have Headache when taking Duavee. It is created by eHealthMe based on reports of 231 people who have side effects when taking Duavee from the FDA, and is updated regularly.

What is Duavee?

Duavee has active ingredients of conjugated estrogens; bazedoxifene. eHealthMe is studying from 235 Duavee users. Check the latest studies of Duavee.

What is Headache?

Headache (pain in head) is found to be associated with 3,750 drugs and 5,772 conditions by eHealthMe. Check the latest studies of Headache.

On Jul, 16, 2026

231 people reported to have side effects when taking Duavee.
Among them, 12 people (5.19%) have Headache.

Among these 12 people:

How long have people been on Duavee when they have Headache? *

What is the gender of people who have Headache when taking Duavee? *

female: 100 %
male: 0.0 %

What is the age of people who have Headache when taking Duavee? *

What are other drugs people take besides Duavee? *

Xyzal: 2 people, 16.67%
Synthroid: 2 people, 16.67%
Singulair: 2 people, 16.67%
Prozac: 2 people, 16.67%
Flonase Allergy Relief: 2 people, 16.67%
Dupixent: 2 people, 16.67%
Albuterol Sulfate: 2 people, 16.67%
Insulin: 1 person, 8.33%
Crestor: 1 person, 8.33%
Allegra: 1 person, 8.33%

What are other side effects people have besides Headache? *

Rashes (redness): 2 people, 16.67%
Skin Haemorrhage (bleeding into skin): 2 people, 16.67%
Dry Skin: 2 people, 16.67%
Nausea (feeling of having an urge to vomit): 2 people, 16.67%
Dizziness: 2 people, 16.67%
Skin Exfoliation (removal of the oldest dead skin cells): 2 people, 16.67%
Skin Fissures (a crack in the skin): 2 people, 16.67%
Head Injury: 2 people, 16.67%
Sleep Disorder: 2 people, 16.67%
Inflammation: 2 people, 16.67%

What are the existing conditions these people have? *

Hot Flush (sudden feelings of heat): 3 people, 25.00%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 16.67%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 2 people, 16.67%
Bone Loss: 2 people, 16.67%
Seasonal Allergy (allergic condition due to certain season): 1 person, 8.33%
Osteoporosis (bones weak and more likely to break): 1 person, 8.33%
Menopausal Symptoms: 1 person, 8.33%
Diabetes: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Duavee and have Headache?

- Check whether Headache is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Duavee:

Duavee (235 reports)

Headache treatments and more:

Headache (756,642 reports)

How severe was Headache and when was it recovered:

Headache in Duavee

Expand to all the drugs that have ingredients of conjugated estrogens; bazedoxifene:

Headache and drugs with ingredients of conjugated estrogens; bazedoxifene (10 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Duavee:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Headache:

Headache (3,750 drugs)

Browse all the conditions that are associated with Headache:

Headache (5,772 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on conjugated estrogens; bazedoxifene (the active ingredients of Duavee) and Duavee (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.