Dulcolax and Acute phosphate nephropathy - a phase IV clinical study of FDA data

Summary:

Acute phosphate nephropathy is reported as a side effect among people who take Dulcolax (bisacodyl), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Avandia, and have Primary pulmonary hypertension.

The phase IV clinical study analyzes which people have Acute phosphate nephropathy when taking Dulcolax. It is created by eHealthMe based on reports of 12,769 people who have side effects when taking Dulcolax from the FDA, and is updated regularly.

What is Dulcolax?

Dulcolax has active ingredients of bisacodyl. It is often used in constipation. eHealthMe is studying from 12,897 Dulcolax users. Check the latest studies of Dulcolax.

What is Acute phosphate nephropathy?

Acute phosphate nephropathy (sudden damage to the kidneys caused by the formation of phosphate crystals) is found to be associated with 34 drugs and 90 conditions by eHealthMe. Check the latest studies of Acute phosphate nephropathy.

On Jul, 20, 2026

12,769 people reported to have side effects when taking Dulcolax.
Among them, 12 people (0.09%) have Acute phosphate nephropathy.

Could Dulcolax cause Acute phosphate nephropathy?

Among these 12 people:

How long have people been on Dulcolax when they have Acute phosphate nephropathy? *

What is the gender of people who have Acute phosphate nephropathy when taking Dulcolax? *

female: 54.55 %
male: 45.45 %

What is the age of people who have Acute phosphate nephropathy when taking Dulcolax? *

What are other drugs people take besides Dulcolax? *

What are other side effects people have besides Acute phosphate nephropathy? *

Acute Kidney Failure: 11 people, 91.67%
Chronic Renal Failure (kidney failure): 8 people, 66.67%
Nephrogenic Anaemia (anaemia due to kidney disease): 6 people, 50.00%
Nausea (feeling of having an urge to vomit): 5 people, 41.67%
Fatigue (feeling of tiredness): 4 people, 33.33%
Diarrhea: 4 people, 33.33%
Weakness: 3 people, 25.00%
Anaemia (lack of blood): 3 people, 25.00%
Dizziness: 3 people, 25.00%
Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 3 people, 25.00%

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 16.67%
Otitis Media (inflammation of the middle ear): 1 person, 8.33%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 1 person, 8.33%
Migraine (headache): 1 person, 8.33%
Indigestion: 1 person, 8.33%
High Blood Pressure: 1 person, 8.33%
Fever: 1 person, 8.33%
Diabetes: 1 person, 8.33%
Asthma: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Dulcolax and have Acute phosphate nephropathy?

- Check whether Acute phosphate nephropathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dulcolax:

Dulcolax (12,897 reports)

Browse all side effects of Dulcolax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Acute phosphate nephropathy:

Acute phosphate nephropathy (34 drugs)

Browse all the conditions that are associated with Acute phosphate nephropathy:

Acute phosphate nephropathy (90 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on bisacodyl (the active ingredients of Dulcolax) and Dulcolax (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.