Duloxetine hydrochloride and Affect lability - a phase IV clinical study of FDA data

Summary:

Affect lability is reported as a side effect among people who take Duloxetine hydrochloride (duloxetine hydrochloride), especially for people who are female, 30-39 old, have been taking the drug for 1 - 6 months also take Cymbalta, and have Pain.

The phase IV clinical study analyzes which people have Affect lability when taking Duloxetine hydrochloride. It is created by eHealthMe based on reports of 16,419 people who have side effects when taking Duloxetine hydrochloride from the FDA, and is updated regularly.

What is Duloxetine hydrochloride?

Duloxetine hydrochloride has active ingredients of duloxetine hydrochloride. It is often used in depression. eHealthMe is studying from 17,411 Duloxetine hydrochloride users. Check the latest studies of Duloxetine hydrochloride.

What is Affect lability?

Affect lability (emotional incontinence) is found to be associated with 667 drugs and 830 conditions by eHealthMe. Check the latest studies of Affect lability.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

16,419 people reported to have side effects when taking Duloxetine hydrochloride.
Among them, 50 people (0.3%) have Affect lability.

Could Duloxetine hydrochloride cause Affect lability?

Among these 50 people:

How long have people been on Duloxetine hydrochloride when they have Affect lability? *

What is the gender of people who have Affect lability when taking Duloxetine hydrochloride? *

female: 68.18 %
male: 31.82 %

What is the age of people who have Affect lability when taking Duloxetine hydrochloride? *

What are other drugs people take besides Duloxetine hydrochloride? *

What are other side effects people have besides Affect lability? *

Dizziness: 31 people, 62.00%
Fatigue (feeling of tiredness): 30 people, 60.00%
Headache (pain in head): 29 people, 58.00%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 26 people, 52.00%
Nausea (feeling of having an urge to vomit): 25 people, 50.00%
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 24 people, 48.00%
Irritability: 24 people, 48.00%
Hyperhidrosis (abnormally increased sweating): 24 people, 48.00%
Suicidal Ideation: 23 people, 46.00%
Insomnia (sleeplessness): 23 people, 46.00%

What are the existing conditions these people have? *

Pain: 9 people, 18.00%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 3 people, 6.00%
Neuralgia (pain in one or more nerves): 3 people, 6.00%
Constipation: 3 people, 6.00%
High Blood Pressure: 2 people, 4.00%
Facial Pain: 2 people, 4.00%
Borderline Personality Disorder: 2 people, 4.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 4.00%
Mood Swings (an extreme or rapid change in mood): 2 people, 4.00%
Back Pain: 1 person, 2.00%

* Approximation only. Some reports may have incomplete information.

Do you take Duloxetine hydrochloride and have Affect lability?

- Check whether Affect lability is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Duloxetine hydrochloride:

Duloxetine hydrochloride (17,411 reports)

Affect lability treatments and more:

Affect lability (13,491 reports)

Browse all side effects of Duloxetine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Affect lability:

Affect lability (667 drugs)

Browse all the conditions that are associated with Affect lability:

Affect lability (830 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on duloxetine hydrochloride (the active ingredients of Duloxetine hydrochloride) and Duloxetine hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.