Duphalac and Hepatitis cholestatic - a phase IV clinical study of FDA data

Summary:

Hepatitis cholestatic is reported as a side effect among people who take Duphalac (lactulose), especially for people who are male, 60+ old, also take Xanax, and have Agitation.

The phase IV clinical study analyzes which people have Hepatitis cholestatic when taking Duphalac. It is created by eHealthMe based on reports of 5,136 people who have side effects when taking Duphalac from the FDA, and is updated regularly.

What is Duphalac?

Duphalac has active ingredients of lactulose. It is often used in constipation. eHealthMe is studying from 5,152 Duphalac users. Check the latest studies of Duphalac.

What is Hepatitis cholestatic?

Hepatitis cholestatic (flow of bile from the liver is slowed or blocked) is found to be associated with 546 drugs and 824 conditions by eHealthMe. Check the latest studies of Hepatitis cholestatic.

On Jul, 20, 2026

5,136 people reported to have side effects when taking Duphalac.
Among them, 19 people (0.37%) have Hepatitis cholestatic.

Could Duphalac cause Hepatitis cholestatic?

Among these 19 people:

What is the gender of people who have Hepatitis cholestatic when taking Duphalac? *

female: 38.89 %
male: 61.11 %

What is the age of people who have Hepatitis cholestatic when taking Duphalac? *

What are other drugs people take besides Duphalac? *

What are other side effects people have besides Hepatitis cholestatic? *

Jaundice - Yellow Skin (a yellowish pigmentation of the skin): 4 people, 21.05%
Fever: 3 people, 15.79%
Hepatic Failure (liver failure): 3 people, 15.79%
Hepatocellular Injury (liver injury): 2 people, 10.53%
Hepatic Steatosis (fatty liver disease): 2 people, 10.53%
Haematuria (presence of blood in urine): 2 people, 10.53%
Hepatomegaly (abnormal enlargement of the liver): 2 people, 10.53%
Biliary Cyst: 2 people, 10.53%
Hepatic Fibrosis (scarring process that represents the liver's response to injury): 2 people, 10.53%
Sphincter Of Oddi Dysfunction (dysfunction of a muscular valve that controls the flow of digestive juices): 2 people, 10.53%

What are the existing conditions these people have? *

Insomnia (sleeplessness): 3 people, 15.79%
Agitation (state of anxiety or nervous excitement): 3 people, 15.79%
Pneumonia: 2 people, 10.53%
Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 2 people, 10.53%
Ventricular Arrhythmia (problem with the rate or rhythm of the heartbeat): 2 people, 10.53%
Spinal Fracture (fracture in one of vertebrae): 2 people, 10.53%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.26%
Osteoporosis (bones weak and more likely to break): 1 person, 5.26%
Mixed Connective Tissue Disease (an autoimmune disease, in which the body's defence system attacks itself): 1 person, 5.26%
Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Duphalac and have Hepatitis cholestatic?

- Check whether Hepatitis cholestatic is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Duphalac:

Duphalac (5,152 reports)

Browse all side effects of Duphalac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatitis cholestatic:

Hepatitis cholestatic (546 drugs)

Browse all the conditions that are associated with Hepatitis cholestatic:

Hepatitis cholestatic (824 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lactulose (the active ingredients of Duphalac) and Duphalac (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.