Duphalac and Oesophagitis - a phase IV clinical study of FDA data

Summary:

Oesophagitis is reported as a side effect among people who take Duphalac (lactulose), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Lactulose, and have Depression.

The phase IV clinical study analyzes which people have Oesophagitis when taking Duphalac. It is created by eHealthMe based on reports of 5,136 people who have side effects when taking Duphalac from the FDA, and is updated regularly.

What is Duphalac?

Duphalac has active ingredients of lactulose. It is often used in constipation. eHealthMe is studying from 5,152 Duphalac users. Check the latest studies of Duphalac.

What is Oesophagitis?

Oesophagitis (inflammation of oesophagus) is found to be associated with 1,180 drugs and 1,066 conditions by eHealthMe. Check the latest studies of Oesophagitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

5,136 people reported to have side effects when taking Duphalac.
Among them, 12 people (0.23%) have Oesophagitis.

Among these 12 people:

How long have people been on Duphalac when they have Oesophagitis? *

What is the gender of people who have Oesophagitis when taking Duphalac? *

female: 55.56 %
male: 44.44 %

What is the age of people who have Oesophagitis when taking Duphalac? *

What are other drugs people take besides Duphalac? *

What are other side effects people have besides Oesophagitis? *

Laryngomalacia (a congenital softening of the tissues of the larynx): 3 people, 25.00%
Polyhydramnios (excess of amniotic fluid in the amniotic sac): 3 people, 25.00%
Monocytosis (an increase in the number of monocytes circulating in the blood): 3 people, 25.00%
Feeding Problem In Newborn: 3 people, 25.00%
Nervous System Disorder (a general class of medical conditions affecting the nervous system): 3 people, 25.00%
Hypotension (abnormally low blood pressure): 3 people, 25.00%
Irritability: 2 people, 16.67%
Hypotonia Neonatal (low muscle tone in neonatal): 2 people, 16.67%
Oesophageal Stenosis (narrowing of oesophagus): 2 people, 16.67%
Leukopenia (less number of white blood cells in blood): 2 people, 16.67%

What are the existing conditions these people have? *

Depression: 4 people, 33.33%
Multiple Myeloma (cancer of the plasma cells): 3 people, 25.00%
Herpes Virus Infection: 3 people, 25.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 25.00%
Oropharyngeal Pain: 2 people, 16.67%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 2 people, 16.67%
Neck Pain: 2 people, 16.67%
Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 2 people, 16.67%
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood): 2 people, 16.67%
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Duphalac and have Oesophagitis?

- Check whether Oesophagitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Duphalac:

Duphalac (5,152 reports)

Oesophagitis treatments and more:

Oesophagitis (19,330 reports)

Browse all side effects of Duphalac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Oesophagitis:

Oesophagitis (1,180 drugs)

Browse all the conditions that are associated with Oesophagitis:

Oesophagitis (1,066 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lactulose (the active ingredients of Duphalac) and Duphalac (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.