Dupixent and Erythema multiforme - a phase IV clinical study of FDA data

Summary:

Erythema multiforme is reported as a side effect among people who take Dupixent (dupilumab), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Neoral, and have Dermatitis atopic.

The phase IV clinical study analyzes which people have Erythema multiforme when taking Dupixent. It is created by eHealthMe based on reports of 257,518 people who have side effects when taking Dupixent from the FDA, and is updated regularly.

What is Dupixent?

Dupixent has active ingredients of dupilumab. eHealthMe is studying from 257,631 Dupixent users. Check the latest studies of Dupixent.

What is Erythema multiforme?

Erythema multiforme (a type of hypersensitivity reaction) is found to be associated with 1,693 drugs and 2,922 conditions by eHealthMe. Check the latest studies of Erythema multiforme.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

257,518 people reported to have side effects when taking Dupixent.
Among them, 65 people (0.03%) have Erythema multiforme.

Could Dupixent cause Erythema multiforme?

Among these 65 people:

How long have people been on Dupixent when they have Erythema multiforme? *

What is the gender of people who have Erythema multiforme when taking Dupixent? *

female: 48 %
male: 52 %

What is the age of people who have Erythema multiforme when taking Dupixent? *

What are other drugs people take besides Dupixent? *

Halog: 2 people, 3.08%
Singulair: 2 people, 3.08%
Protopic: 2 people, 3.08%
Neoral: 2 people, 3.08%
Vitamin C: 1 person, 1.54%
Amlodipine: 1 person, 1.54%
Asa: 1 person, 1.54%
Bactrim: 1 person, 1.54%
Betamethasone Sodium Phosphate: 1 person, 1.54%
Bevespi Aerosphere: 1 person, 1.54%

What are other side effects people have besides Erythema multiforme? *

Rashes (redness): 10 people, 15.38%
Itching: 8 people, 12.31%
Skin Exfoliation (removal of the oldest dead skin cells): 6 people, 9.23%
Pain: 5 people, 7.69%
Oedema (fluid collection in tissue): 4 people, 6.15%
Burning Sensation: 4 people, 6.15%
Lip Swelling: 3 people, 4.62%
Toxic Skin Eruption (skin breakdown due to toxic substance): 3 people, 4.62%
Asthma: 3 people, 4.62%
Skin Fissures (a crack in the skin): 3 people, 4.62%

What are the existing conditions these people have? *

Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 44 people, 67.69%
Asthma: 3 people, 4.62%
Nasal Polyps (masses that develop in the lining of the nose): 2 people, 3.08%
Itching: 2 people, 3.08%
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 2 people, 3.08%
Constipation: 2 people, 3.08%
Toxic Skin Eruption (skin breakdown due to toxic substance): 1 person, 1.54%
High Blood Pressure: 1 person, 1.54%
Food Allergy: 1 person, 1.54%
Dyslipidaemia (abnormal amount of lipids): 1 person, 1.54%

* Approximation only. Some reports may have incomplete information.

Do you take Dupixent and have Erythema multiforme?

- Check whether Erythema multiforme is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dupixent:

Dupixent (257,631 reports)

Browse all side effects of Dupixent:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Erythema multiforme:

Erythema multiforme (1,693 drugs)

Browse all the conditions that are associated with Erythema multiforme:

Erythema multiforme (2,922 conditions)

Related publications that referenced our studies

Tognetti L, Giorgini S, Lotti T, "Erythema multiforme-like eruption from a slimming drug preparation cutaneous adverse drug reaction", Indian dermatology online journal, 2011 Jan .
Tognetti L, Giorgini S, Lotti T, "Erythema multiforme-like eruption from a slimming drug preparation cutaneous adverse drug reaction", Indian dermatology online journal, 2011 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on dupilumab (the active ingredients of Dupixent) and Dupixent (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.