Dupixent and Tonsillolith - a phase IV clinical study of FDA data

Summary:

Tonsillolith is reported as a side effect among people who take Dupixent (dupilumab), especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months also take Zantac, and have Eczema.

The phase IV clinical study analyzes which people have Tonsillolith when taking Dupixent. It is created by eHealthMe based on reports of 257,518 people who have side effects when taking Dupixent from the FDA, and is updated regularly.

What is Dupixent?

Dupixent has active ingredients of dupilumab. eHealthMe is studying from 257,631 Dupixent users. Check the latest studies of Dupixent.

What is Tonsillolith?

Tonsillolith (tonsil stones) is found to be associated with 11 drugs and 78 conditions by eHealthMe. Check the latest studies of Tonsillolith.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

257,518 people reported to have side effects when taking Dupixent.
Among them, 12 people (0.0%) have Tonsillolith.

Among these 12 people:

How long have people been on Dupixent when they have Tonsillolith? *

What is the gender of people who have Tonsillolith when taking Dupixent? *

female: 55.56 %
male: 44.44 %

What is the age of people who have Tonsillolith when taking Dupixent? *

What are other drugs people take besides Dupixent? *

What are other side effects people have besides Tonsillolith? *

Oropharyngeal Pain: 4 people, 33.33%
Sinusitis (inflammation of sinus): 2 people, 16.67%
Injection Site Pain: 2 people, 16.67%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 2 people, 16.67%
Nasal Polyps (masses that develop in the lining of the nose): 1 person, 8.33%
Canker Sores (painful, open sore in the mouth): 1 person, 8.33%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 1 person, 8.33%
Fever: 1 person, 8.33%
Furuncle (infection of the hair follicle): 1 person, 8.33%
Hypoaesthesia (reduced sense of touch or sensation): 1 person, 8.33%

What are the existing conditions these people have? *

Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 3 people, 25.00%
Sinusitis (inflammation of sinus): 2 people, 16.67%
Nasal Polyps (masses that develop in the lining of the nose): 2 people, 16.67%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 2 people, 16.67%
Asthma: 2 people, 16.67%
Eosinophilic Esophagitis (Eosinophilic esophagitis (EoE) is an allergic inflammatory condition of the esophagus that involves eosinophils, a type of white blood cell): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Dupixent and have Tonsillolith?

- Check whether Tonsillolith is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dupixent:

Dupixent (257,631 reports)

Tonsillolith treatments and more:

Tonsillolith (154 reports)

Browse all side effects of Dupixent:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Tonsillolith:

Tonsillolith (11 drugs)

Browse all the conditions that are associated with Tonsillolith:

Tonsillolith (78 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on dupilumab (the active ingredients of Dupixent) and Dupixent (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.