Duragesic and Exhaustion, fatigue, lethargy, tiredness, weariness - a phase IV clinical study of FDA data

Summary:

Exhaustion, fatigue, lethargy, tiredness, weariness is reported as a side effect among people who take Duragesic (fentanyl), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Zometa, and have Pain.

The phase IV clinical study analyzes which people have Exhaustion, fatigue, lethargy, tiredness, weariness when taking Duragesic. It is created by eHealthMe based on reports of 66,376 people who have side effects when taking Duragesic from the FDA, and is updated regularly.

What is Duragesic?

Duragesic has active ingredients of fentanyl. eHealthMe is studying from 66,597 Duragesic users. Check the latest studies of Duragesic.

What is Exhaustion, fatigue, lethargy, tiredness, weariness?

Exhaustion, fatigue, lethargy, tiredness, weariness is found to be associated with 5,308 drugs and 6,696 conditions by eHealthMe. Check the latest studies of Exhaustion, fatigue, lethargy, tiredness, weariness.



On Feb, 05, 2026

66,376 people reported to have side effects when taking Duragesic.
Among them, 1,974 people (2.97%) have Exhaustion, fatigue, lethargy, tiredness, weariness.

Could Duragesic cause Exhaustion, fatigue, lethargy, tiredness, weariness?

Among these 1,974 people:

How long have people been on Duragesic when they have Exhaustion, fatigue, lethargy, tiredness, weariness? *

What is the gender of people who have Exhaustion, fatigue, lethargy, tiredness, weariness when taking Duragesic? *

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What is the age of people who have Exhaustion, fatigue, lethargy, tiredness, weariness when taking Duragesic? *

What are other drugs people take besides Duragesic? *

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What are other side effects people have besides Exhaustion, fatigue, lethargy, tiredness, weariness? *

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What are the existing conditions these people have? *

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* Approximation only. Some reports may have incomplete information.

Do you take Duragesic and have Exhaustion, fatigue, lethargy, tiredness, weariness?

- Check whether Exhaustion, fatigue, lethargy, tiredness, weariness is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Duragesic:

Exhaustion, fatigue, lethargy, tiredness, weariness treatments and more:

How severe was Exhaustion, fatigue, lethargy, tiredness, weariness and when was it recovered:

Expand to all the drugs that have ingredients of fentanyl:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Duragesic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Exhaustion, fatigue, lethargy, tiredness, weariness:

Browse all the conditions that are associated with Exhaustion, fatigue, lethargy, tiredness, weariness:


How the study uses the data?

The study uses data from the FDA. It is based on fentanyl (the active ingredients of Duragesic) and Duragesic (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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