Duramorph and Anhedonia - a phase IV clinical study of FDA data

Summary:

Anhedonia is reported as a side effect among people who take Duramorph (morphine sulfate), especially for people who are male, 50-59 old, have been taking the drug for 1 - 6 months also take Reglan, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Anhedonia when taking Duramorph. It is created by eHealthMe based on reports of 362 people who have side effects when taking Duramorph from the FDA, and is updated regularly.

What is Duramorph?

Duramorph has active ingredients of morphine sulfate. eHealthMe is studying from 367 Duramorph users. Check the latest studies of Duramorph.

What is Anhedonia?

Anhedonia (inability to experience pleasure from activities usually found enjoyable) is found to be associated with 1,509 drugs and 1,281 conditions by eHealthMe. Check the latest studies of Anhedonia.



On Jul, 28, 2026

362 people reported to have side effects when taking Duramorph.
Among them, 21 people (5.8%) have Anhedonia.

Could Duramorph cause Anhedonia?

Among these 21 people:

How long have people been on Duramorph when they have Anhedonia? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Anhedonia when taking Duramorph? *

  • female: 4.76 %
  • male: 95.24 %

What is the age of people who have Anhedonia when taking Duramorph? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 4.76 %
  • 50-59: 90.48 %
  • 60+: 4.76 %

What are other drugs people take besides Duramorph? *

  1. Zometa: 20 people, 95.24%
  2. Tenormin: 20 people, 95.24%
  3. Lioresal: 20 people, 95.24%
  4. Neurontin: 20 people, 95.24%
  5. Lidoderm: 20 people, 95.24%
  6. Lantus: 20 people, 95.24%
  7. Oxycontin: 20 people, 95.24%
  8. Percocet: 20 people, 95.24%
  9. Prilosec: 20 people, 95.24%
  10. Reglan: 20 people, 95.24%

What are other side effects people have besides Anhedonia? *

  1. Stress And Anxiety: 21 people, 100.00%
  2. Emotional Distress: 21 people, 100.00%
  3. Pain: 21 people, 100.00%
  4. Hypophagia (reduced food intake): 20 people, 95.24%
  5. Discomfort: 20 people, 95.24%
  6. Depression: 20 people, 95.24%
  7. Deformity (disfigurement): 20 people, 95.24%
  8. Injury: 20 people, 95.24%
  9. Myelitis Transverse (a neurological condition consisting of an inflammatory process of the spinal cord): 17 people, 80.95%
  10. Intervertebral Disc Degeneration (spinal disc degeneration): 16 people, 76.19%

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 20 people, 95.24%
  2. Pain: 1 person, 4.76%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 4.76%
  4. Inflammation: 1 person, 4.76%
  5. Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 1 person, 4.76%
  6. Hiv Infection: 1 person, 4.76%
  7. High Blood Pressure: 1 person, 4.76%
  8. High Blood Cholesterol: 1 person, 4.76%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 4.76%
  10. Fungal Infection: 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Duramorph and have Anhedonia?

- Check whether Anhedonia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Duramorph:

Anhedonia treatments and more:

How severe was Anhedonia and when was it recovered:

Expand to all the drugs that have ingredients of morphine sulfate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Duramorph:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Anhedonia:

Browse all the conditions that are associated with Anhedonia:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on morphine sulfate (the active ingredients of Duramorph) and Duramorph (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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