Dymista and Nasal septum deviation - a phase IV clinical study of FDA data

Summary:

Nasal septum deviation is reported as a side effect among people who take Dymista (azelastine hydrochloride; fluticasone propionate), especially for people who are female, 50-59 old, also take Cymbalta, and have Narcolepsy.

The phase IV clinical study analyzes which people have Nasal septum deviation when taking Dymista. It is created by eHealthMe based on reports of 4,296 people who have side effects when taking Dymista from the FDA, and is updated regularly.

What is Dymista?

Dymista has active ingredients of azelastine hydrochloride; fluticasone propionate. It is often used in allergies. eHealthMe is studying from 4,407 Dymista users. Check the latest studies of Dymista.

What is Nasal septum deviation?

Nasal septum deviation (deviated nasal septum) is found to be associated with 473 drugs and 463 conditions by eHealthMe. Check the latest studies of Nasal septum deviation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

4,296 people reported to have side effects when taking Dymista.
Among them, 12 people (0.28%) have Nasal septum deviation.

Could Dymista cause Nasal septum deviation?

Among these 12 people:

What is the gender of people who have Nasal septum deviation when taking Dymista? *

female: 81.82 %
male: 18.18 %

What is the age of people who have Nasal septum deviation when taking Dymista? *

What are other drugs people take besides Dymista? *

What are other side effects people have besides Nasal septum deviation? *

Migraine (headache): 4 people, 33.33%
Fall: 4 people, 33.33%
Arthropathy: 3 people, 25.00%
Trigger Finger: 3 people, 25.00%
Toothaches (tooth pain): 3 people, 25.00%
Plantar Fasciitis (painful inflammatory process of the plantar fascia): 3 people, 25.00%
Wrist Fracture: 2 people, 16.67%
Infusion Related Reaction: 2 people, 16.67%
Muscle Aches (muscle pain): 2 people, 16.67%
Multiple Allergies (allergy to multiple agents): 2 people, 16.67%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 33.33%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 25.00%
Insomnia (sleeplessness): 2 people, 16.67%
Immunodeficiency Common Variable: 2 people, 16.67%
Allergic Rhinitis: 2 people, 16.67%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 8.33%
Stress And Anxiety: 1 person, 8.33%
Pain: 1 person, 8.33%
High Blood Pressure: 1 person, 8.33%
Eye Pruritus (eye itching): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Dymista and have Nasal septum deviation?

- Check whether Nasal septum deviation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dymista:

Dymista (4,407 reports)

Nasal septum deviation treatments and more:

Nasal septum deviation (2,978 reports)

How severe was Nasal septum deviation and when was it recovered:

Nasal septum deviation in Dymista

Expand to all the drugs that have ingredients of azelastine hydrochloride; fluticasone propionate:

Nasal septum deviation and drugs with ingredients of azelastine hydrochloride; fluticasone propionate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Dymista:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nasal septum deviation:

Nasal septum deviation (473 drugs)

Browse all the conditions that are associated with Nasal septum deviation:

Nasal septum deviation (463 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on azelastine hydrochloride; fluticasone propionate (the active ingredients of Dymista) and Dymista (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.