Efavirenz and Left ventricular dysfunction - a phase IV clinical study of FDA data

Summary:

Left ventricular dysfunction is reported as a side effect among people who take Efavirenz (efavirenz), especially for people who are male, 40-49 old, also take Lamivudine, and have Cryptococcosis.

The phase IV clinical study analyzes which people have Left ventricular dysfunction when taking Efavirenz. It is created by eHealthMe based on reports of 15,449 people who have side effects when taking Efavirenz from the FDA, and is updated regularly.

What is Efavirenz?

Efavirenz has active ingredients of efavirenz. It is often used in hiv infection. eHealthMe is studying from 15,501 Efavirenz users. Check the latest studies of Efavirenz.

What is Left ventricular dysfunction?

Left ventricular dysfunction is found to be associated with 888 drugs and 793 conditions by eHealthMe. Check the latest studies of Left ventricular dysfunction.

On Aug, 09, 2026

15,449 people reported to have side effects when taking Efavirenz.
Among them, 13 people (0.08%) have Left ventricular dysfunction.

Could Efavirenz cause Left ventricular dysfunction?

Among these 13 people:

What is the gender of people who have Left ventricular dysfunction when taking Efavirenz? *

female: 30 %
male: 70 %

What is the age of people who have Left ventricular dysfunction when taking Efavirenz? *

What are other drugs people take besides Efavirenz? *

Abacavir And Lamivudine: 3 people, 23.08%
Lamivudine: 3 people, 23.08%
Stavudine: 2 people, 15.38%
Dexamethasone: 1 person, 7.69%
Decadron: 1 person, 7.69%
Darunavir: 1 person, 7.69%
Cytoxan: 1 person, 7.69%
Cozaar: 1 person, 7.69%
Cefzil: 1 person, 7.69%
Azithromycin: 1 person, 7.69%

What are other side effects people have besides Left ventricular dysfunction? *

Acute Myocardial Infarction (acute heart attack): 8 people, 61.54%
Mitochondrial Toxicity (a condition in which the mitochondria of a body's cells become damaged or decline significantly in number;): 2 people, 15.38%
Diarrhea: 2 people, 15.38%
Weight Loss: 1 person, 7.69%
Excessive Or Unwanted Hair In Women: 1 person, 7.69%
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body): 1 person, 7.69%
Drug Intolerance (drug sensitivity): 1 person, 7.69%
Dyslipidaemia (abnormal amount of lipids): 1 person, 7.69%
Dyspnea (difficult or laboured breathing): 1 person, 7.69%
Ear Pain: 1 person, 7.69%

What are the existing conditions these people have? *

Cryptococcosis (potentially fatal fungal disease): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Efavirenz and have Left ventricular dysfunction?

- Check whether Left ventricular dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Efavirenz:

Efavirenz (15,501 reports)

Browse all side effects of Efavirenz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Left ventricular dysfunction:

Left ventricular dysfunction (889 drugs)

Browse all the conditions that are associated with Left ventricular dysfunction:

Left ventricular dysfunction (793 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on efavirenz (the active ingredients of Efavirenz) and Efavirenz (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.