Effexor xr and Fracture nonunion - a phase IV clinical study of FDA data

Summary:

Fracture nonunion is reported as a side effect among people who take Effexor xr (venlafaxine hydrochloride), especially for people who are female, 60+ old, also take Fosamax, and have Osteoporosis.

The phase IV clinical study analyzes which people have Fracture nonunion when taking Effexor xr. It is created by eHealthMe based on reports of 31,325 people who have side effects when taking Effexor xr from the FDA, and is updated regularly.

What is Effexor xr?

Effexor xr has active ingredients of venlafaxine hydrochloride. It is often used in depression. eHealthMe is studying from 35,233 Effexor xr users. Check the latest studies of Effexor xr.

What is Fracture nonunion?

Fracture nonunion (permanent failure of healing following a broken bone) is found to be associated with 312 drugs and 369 conditions by eHealthMe. Check the latest studies of Fracture nonunion.



On Jul, 14, 2026

31,325 people reported to have side effects when taking Effexor xr.
Among them, 14 people (0.04%) have Fracture nonunion.

Could Effexor xr cause Fracture nonunion?

Among these 14 people:

What is the gender of people who have Fracture nonunion when taking Effexor xr? *

  • female: 83.33 %
  • male: 16.67 %

What is the age of people who have Fracture nonunion when taking Effexor xr? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 50 %
  • 50-59: 0.0 %
  • 60+: 50 %

What are other drugs people take besides Effexor xr? *

  1. Fosamax: 11 people, 78.57%
  2. Allegra: 4 people, 28.57%
  3. Altace: 4 people, 28.57%
  4. Avandia: 4 people, 28.57%
  5. Glipizide: 4 people, 28.57%
  6. Glucophage Xr: 4 people, 28.57%
  7. Metformin: 4 people, 28.57%
  8. Lamivudine: 2 people, 14.29%
  9. Norvir: 2 people, 14.29%
  10. Actonel: 2 people, 14.29%

What are other side effects people have besides Fracture nonunion? *

  1. Femur Fracture: 11 people, 78.57%
  2. High Blood Pressure: 9 people, 64.29%
  3. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 7 people, 50.00%
  4. Rib Fracture: 7 people, 50.00%
  5. Device Failure: 7 people, 50.00%
  6. Fall: 6 people, 42.86%
  7. Spinal Osteoarthritis (joint cartilage loss in spine): 6 people, 42.86%
  8. Impaired Healing: 6 people, 42.86%
  9. High Blood Cholesterol: 6 people, 42.86%
  10. Foot Fracture: 5 people, 35.71%

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 11 people, 78.57%
  2. Osteopenia (a condition where bone mineral density is lower than normal): 4 people, 28.57%
  3. Diabetes: 4 people, 28.57%
  4. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 2 people, 14.29%
  5. Hiv Test Positive: 2 people, 14.29%
  6. Bipolar Disorder (mood disorder): 2 people, 14.29%
  7. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Effexor xr and have Fracture nonunion?

- Check whether Fracture nonunion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Effexor xr:

Fracture nonunion treatments and more:

How severe was Fracture nonunion and when was it recovered:

Expand to all the drugs that have ingredients of venlafaxine hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Effexor xr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fracture nonunion:

Browse all the conditions that are associated with Fracture nonunion:


How the study uses the data?

The study uses data from the FDA. It is based on venlafaxine hydrochloride (the active ingredients of Effexor xr) and Effexor xr (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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