Effexor and Autoimmune hepatitis - a phase IV clinical study of FDA data

Summary:

Autoimmune hepatitis is reported as a side effect among people who take Effexor (venlafaxine hydrochloride), especially for people who are female, 40-49 old, have been taking the drug for 6 - 12 months also take Tracleer, and have Primary pulmonary hypertension.

The phase IV clinical study analyzes which people have Autoimmune hepatitis when taking Effexor. It is created by eHealthMe based on reports of 92,291 people who have side effects when taking Effexor from the FDA, and is updated regularly.

What is Effexor?

Effexor has active ingredients of venlafaxine hydrochloride. It is often used in depression. eHealthMe is studying from 99,493 Effexor users. Check the latest studies of Effexor.

What is Autoimmune hepatitis?

Autoimmune hepatitis is found to be associated with 587 drugs and 818 conditions by eHealthMe. Check the latest studies of Autoimmune hepatitis.

On Aug, 02, 2026

92,291 people reported to have side effects when taking Effexor.
Among them, 37 people (0.04%) have Autoimmune hepatitis.

Could Effexor cause Autoimmune hepatitis?

Among these 37 people:

How long have people been on Effexor when they have Autoimmune hepatitis? *

What is the gender of people who have Autoimmune hepatitis when taking Effexor? *

female: 67.57 %
male: 32.43 %

What is the age of people who have Autoimmune hepatitis when taking Effexor? *

What are other drugs people take besides Effexor? *

What are other side effects people have besides Autoimmune hepatitis? *

Hepatic Enzyme Increased: 10 people, 27.03%
Malaise (a feeling of general discomfort or uneasiness): 8 people, 21.62%
Aspartate Aminotransferase Increased: 6 people, 16.22%
Alanine Aminotransferase Increased: 6 people, 16.22%
Liver Function Test Abnormal: 6 people, 16.22%
Cytolytic Hepatitis (dissolution or destruction of a liver cell): 6 people, 16.22%
Cholestasis (a condition where bile cannot flow from the liver to the duodenum): 6 people, 16.22%
Blood Bilirubin Increased: 5 people, 13.51%
Gamma-Glutamyltransferase Increased: 5 people, 13.51%
Jaundice - Yellow Skin (a yellowish pigmentation of the skin): 5 people, 13.51%

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 7 people, 18.92%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 5 people, 13.51%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 10.81%
Drowsiness: 3 people, 8.11%
Gait Disturbance: 3 people, 8.11%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 8.11%
Irritable Bowel Syndrome: 3 people, 8.11%
Reiter's Syndrome (a type of reactive arthritis, it happens as a reaction to a bacterial infection): 3 people, 8.11%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 5.41%
Fatigue (feeling of tiredness): 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

Do you take Effexor and have Autoimmune hepatitis?

- Check whether Autoimmune hepatitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Effexor:

Effexor (99,493 reports)

Browse all side effects of Effexor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Autoimmune hepatitis:

Autoimmune hepatitis (587 drugs)

Browse all the conditions that are associated with Autoimmune hepatitis:

Autoimmune hepatitis (818 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on venlafaxine hydrochloride (the active ingredients of Effexor) and Effexor (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.