Effexor and Rectal prolapse - a phase IV clinical study of FDA data

Summary:

Rectal prolapse is reported as a side effect among people who take Effexor (venlafaxine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Remeron, and have Narcolepsy.

The phase IV clinical study analyzes which people have Rectal prolapse when taking Effexor. It is created by eHealthMe based on reports of 92,291 people who have side effects when taking Effexor from the FDA, and is updated regularly.

What is Effexor?

Effexor has active ingredients of venlafaxine hydrochloride. It is often used in depression. eHealthMe is studying from 99,496 Effexor users. Check the latest studies of Effexor.

What is Rectal prolapse?

Rectal prolapse (falling of rectum from normal place) is found to be associated with 307 drugs and 341 conditions by eHealthMe. Check the latest studies of Rectal prolapse.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

92,291 people reported to have side effects when taking Effexor.
Among them, 24 people (0.03%) have Rectal prolapse.

Among these 24 people:

How long have people been on Effexor when they have Rectal prolapse? *

What is the gender of people who have Rectal prolapse when taking Effexor? *

female: 100 %
male: 0.0 %

What is the age of people who have Rectal prolapse when taking Effexor? *

What are other drugs people take besides Effexor? *

What are other side effects people have besides Rectal prolapse? *

Neck Pain: 4 people, 16.67%
Pain In Extremity: 4 people, 16.67%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 4 people, 16.67%
Constipation: 4 people, 16.67%
Rectal Haemorrhage (bleeding from anus): 4 people, 16.67%
Peripheral Swelling: 4 people, 16.67%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 4 people, 16.67%
Osteoporosis (bones weak and more likely to break): 4 people, 16.67%
Suicidal Ideation: 4 people, 16.67%
Pain: 4 people, 16.67%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 16.67%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 16.67%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 12.50%
Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 2 people, 8.33%
Disturbance In Attention: 2 people, 8.33%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 8.33%
Asperger's Disorder (autism spectrum disorder that affects language and behavioural development in children): 2 people, 8.33%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 8.33%
Osteoporosis (bones weak and more likely to break): 2 people, 8.33%
High Blood Cholesterol: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Effexor and have Rectal prolapse?

- Check whether Rectal prolapse is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Effexor:

Effexor (99,496 reports)

Rectal prolapse treatments and more:

Rectal prolapse (1,711 reports)

Browse all side effects of Effexor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rectal prolapse:

Rectal prolapse (307 drugs)

Browse all the conditions that are associated with Rectal prolapse:

Rectal prolapse (341 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on venlafaxine hydrochloride (the active ingredients of Effexor) and Effexor (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.