Elavil and Bladder dysfunction - a phase IV clinical study of FDA data

Summary:

Bladder dysfunction is reported as a side effect among people who take Elavil (amitriptyline hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for 6 - 12 months also take Cymbalta, and have Breast cancer.

The phase IV clinical study analyzes which people have Bladder dysfunction when taking Elavil. It is created by eHealthMe based on reports of 19,133 people who have side effects when taking Elavil from the FDA, and is updated regularly.

What is Elavil?

Elavil has active ingredients of amitriptyline hydrochloride. It is often used in depression. eHealthMe is studying from 20,723 Elavil users. Check the latest studies of Elavil.

What is Bladder dysfunction?

Bladder dysfunction is found to be associated with 257 drugs and 271 conditions by eHealthMe. Check the latest studies of Bladder dysfunction.



On Jan, 15, 2026

19,133 people reported to have side effects when taking Elavil.
Among them, 13 people (0.07%) have Bladder dysfunction.

Could Elavil cause Bladder dysfunction?

Among these 13 people:

How long have people been on Elavil when they have Bladder dysfunction? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 100 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Bladder dysfunction when taking Elavil? *

  • female: 84.62 %
  • male: 15.38 %

What is the age of people who have Bladder dysfunction when taking Elavil? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 15.38 %
  • 50-59: 69.23 %
  • 60+: 15.38 %

What are other drugs people take besides Elavil? *

  1. Neurontin: 11 people, 84.62%
  2. Cymbalta: 11 people, 84.62%
  3. Zometa: 10 people, 76.92%
  4. Oxycontin: 10 people, 76.92%
  5. Rocephin: 9 people, 69.23%
  6. Dexamethasone: 9 people, 69.23%
  7. Percocet: 9 people, 69.23%
  8. Vicodin: 8 people, 61.54%
  9. Doxycycline: 8 people, 61.54%
  10. Lasix: 8 people, 61.54%

What are other side effects people have besides Bladder dysfunction? *

  1. Muscle Aches (muscle pain): 11 people, 84.62%
  2. Pain: 11 people, 84.62%
  3. Memory Loss: 11 people, 84.62%
  4. Diarrhea: 11 people, 84.62%
  5. Bone Disorder: 10 people, 76.92%
  6. Fall: 10 people, 76.92%
  7. Pain In Extremity: 10 people, 76.92%
  8. Osteonecrosis Of Jaw (death of bone of jaw): 10 people, 76.92%
  9. Infection: 10 people, 76.92%
  10. Urinary Tract Infection: 10 people, 76.92%

What are the existing conditions these people have? *

  1. Fibromyalgia (a long-term condition which causes pain all over the body): 8 people, 61.54%
  2. Breast Cancer: 8 people, 61.54%
  3. Neuropathy Peripheral (surface nerve damage): 7 people, 53.85%
  4. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 7 people, 53.85%
  5. Pain: 2 people, 15.38%
  6. Osteoporosis (bones weak and more likely to break): 2 people, 15.38%
  7. Spinal Pain (pain in spine): 1 person, 7.69%
  8. Sleep Disorder: 1 person, 7.69%
  9. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.69%
  10. Neuralgia (pain in one or more nerves): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Elavil and have Bladder dysfunction?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Elavil:

Bladder dysfunction treatments and more:

How severe was Bladder dysfunction and when was it recovered:

Expand to all the drugs that have ingredients of amitriptyline hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Elavil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bladder dysfunction:

Browse all the conditions that are associated with Bladder dysfunction:

Drugs similar to Elavil and Bladder dysfunction :

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on amitriptyline hydrochloride (the active ingredients of Elavil) and Elavil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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