Elavil and Panic attacks - a phase IV clinical study of FDA data

Summary:

Panic attacks is reported as a side effect among people who take Elavil (amitriptyline hydrochloride), especially for people who are female, 40-49 old, have been taking the drug for 2 - 5 years also take Cymbalta, and have Pain.

The phase IV clinical study analyzes which people have Panic attacks when taking Elavil. It is created by eHealthMe based on reports of 19,133 people who have side effects when taking Elavil from the FDA, and is updated regularly.

What is Elavil?

Elavil has active ingredients of amitriptyline hydrochloride. It is often used in depression. eHealthMe is studying from 20,723 Elavil users. Check the latest studies of Elavil.

What is Panic attacks?

Panic attacks is found to be associated with 2,582 drugs and 2,067 conditions by eHealthMe. Check the latest studies of Panic attacks.



On Nov, 20, 2025

19,133 people reported to have side effects when taking Elavil.
Among them, 255 people (1.33%) have Panic attacks.

Could Elavil cause Panic attacks?

Among these 255 people:

How long have people been on Elavil when they have Panic attacks? *

  • < 1 month: 9.09 %
  • 1 - 6 months: 27.27 %
  • 6 - 12 months: 18.18 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 27.27 %
  • 5 - 10 years: 18.18 %
  • 10+ years: 0.0 %

What is the gender of people who have Panic attacks when taking Elavil? *

  • female: 71.77 %
  • male: 28.23 %

What is the age of people who have Panic attacks when taking Elavil? *

  • 0-1: 0.47 %
  • 2-9: 0.0 %
  • 10-19: 0.47 %
  • 20-29: 3.32 %
  • 30-39: 22.27 %
  • 40-49: 29.86 %
  • 50-59: 23.22 %
  • 60+: 20.38 %

What are other drugs people take besides Elavil? *

  1. Cymbalta: 65 people, 25.49%
  2. Oxycontin: 63 people, 24.71%
  3. Actemra: 53 people, 20.78%
  4. Xanax: 49 people, 19.22%
  5. Ativan: 48 people, 18.82%
  6. Synthroid: 45 people, 17.65%
  7. Pantoprazole: 45 people, 17.65%
  8. Morphine Sulfate: 45 people, 17.65%
  9. Ventolin: 40 people, 15.69%
  10. Acetaminophen: 39 people, 15.29%

What are other side effects people have besides Panic attacks? *

  1. Stress And Anxiety: 161 people, 63.14%
  2. Weakness: 138 people, 54.12%
  3. Headache (pain in head): 126 people, 49.41%
  4. Nausea (feeling of having an urge to vomit): 125 people, 49.02%
  5. Hypoaesthesia (reduced sense of touch or sensation): 125 people, 49.02%
  6. Fatigue (feeling of tiredness): 114 people, 44.71%
  7. Dyspnea (difficult or laboured breathing): 109 people, 42.75%
  8. Pain: 108 people, 42.35%
  9. Pain In Extremity: 105 people, 41.18%
  10. Joint Pain: 96 people, 37.65%

What are the existing conditions these people have? *

  1. Pain: 81 people, 31.76%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 58 people, 22.75%
  3. Sleep Disorder: 34 people, 13.33%
  4. Stress And Anxiety: 25 people, 9.80%
  5. High Blood Pressure: 22 people, 8.63%
  6. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 15 people, 5.88%
  7. Bone Disorder: 15 people, 5.88%
  8. Muscle Spasms (muscle contraction): 13 people, 5.10%
  9. Fatigue (feeling of tiredness): 12 people, 4.71%
  10. Fibromyalgia (a long-term condition which causes pain all over the body): 10 people, 3.92%

* Approximation only. Some reports may have incomplete information.

Do you take Elavil and have Panic attacks?

- Check whether Panic attacks is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Elavil:

Panic attacks treatments and more:

How severe was Panic attacks and when was it recovered:

Expand to all the drugs that have ingredients of amitriptyline hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Elavil side effects:

Browse all side effects of Elavil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Panic attacks:

Browse all the drugs that are associated with Panic attacks:

Common conditions associated with Panic attacks:

Browse all the conditions that are associated with Panic attacks:

Drugs similar to Elavil and Panic attacks :

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on amitriptyline hydrochloride (the active ingredients of Elavil) and Elavil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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