Elavil and Walking during sleep - a phase IV clinical study of FDA data

Summary:

Walking during sleep is reported as a side effect among people who take Elavil (amitriptyline hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Seroquel, and have Pain.

The phase IV clinical study analyzes which people have Walking during sleep when taking Elavil. It is created by eHealthMe based on reports of 19,133 people who have side effects when taking Elavil from the FDA, and is updated regularly.

What is Elavil?

Elavil has active ingredients of amitriptyline hydrochloride. It is often used in depression. eHealthMe is studying from 20,723 Elavil users. Check the latest studies of Elavil.

What is Walking during sleep?

Walking during sleep is found to be associated with 920 drugs and 1,107 conditions by eHealthMe. Check the latest studies of Walking during sleep.

On Jan, 30, 2026

19,133 people reported to have side effects when taking Elavil.
Among them, 37 people (0.19%) have Walking during sleep.

Could Elavil cause Walking during sleep?

Among these 37 people:

How long have people been on Elavil when they have Walking during sleep? *

What is the gender of people who have Walking during sleep when taking Elavil? *

female: 64.86 %
male: 35.14 %

What is the age of people who have Walking during sleep when taking Elavil? *

What are other drugs people take besides Elavil? *

What are other side effects people have besides Walking during sleep? *

Memory Loss: 23 people, 62.16%
Stress And Anxiety: 20 people, 54.05%
Confusional State: 18 people, 48.65%
Headache (pain in head): 17 people, 45.95%
Fatigue (feeling of tiredness): 16 people, 43.24%
Malaise (a feeling of general discomfort or uneasiness): 15 people, 40.54%
Pain In Extremity: 15 people, 40.54%
Back Pain: 14 people, 37.84%
Joint Pain: 14 people, 37.84%
Oedema Peripheral (superficial swelling): 14 people, 37.84%

What are the existing conditions these people have? *

Pain: 13 people, 35.14%
Prostate Cancer: 9 people, 24.32%
Bone Density Abnormal: 9 people, 24.32%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 10.81%
Sleep Disorder: 4 people, 10.81%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 10.81%
Headache (pain in head): 3 people, 8.11%
Drug Dependence: 2 people, 5.41%
Affective Disorder (mental disorder): 2 people, 5.41%
Compulsions (performing an act persistently and repetitively): 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

Do you take Elavil and have Walking during sleep?

- Check whether Walking during sleep is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Elavil:

Elavil (20,723 reports)

Browse all side effects of Elavil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Walking during sleep:

Walking during sleep (920 drugs)

Browse all the conditions that are associated with Walking during sleep:

Walking during sleep (1,107 conditions)

Drugs similar to Elavil and Walking during sleep :

Related publications that referenced our studies

Li W, Lamichhane J, "From Heartbreak to Left Bundle Branch Block: A Case of Amitriptyline Overdose", American Journal of Therapeutics, 2017 Sep .
Li W, Lamichhane J, "From Heartbreak to Left Bundle Branch Block: A Case of Amitriptyline Overdose", American Journal of Therapeutics, 2017 Sep .

How the study uses the data?

The study uses data from the FDA. It is based on amitriptyline hydrochloride (the active ingredients of Elavil) and Elavil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.