Eliquis and Hypercalcaemia - a phase IV clinical study of FDA data

Summary:

Hypercalcaemia is reported as a side effect among people who take Eliquis (apixaban), especially for people who are female, 60+ old, also take Metformin, and have High blood pressure.

The phase IV clinical study analyzes which people have Hypercalcaemia when taking Eliquis. It is created by eHealthMe based on reports of 189,425 people who have side effects when taking Eliquis from the FDA, and is updated regularly.

What is Eliquis?

Eliquis has active ingredients of apixaban. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 191,859 Eliquis users. Check the latest studies of Eliquis.

What is Hypercalcaemia?

Hypercalcaemia (elevated calcium (ca+) level in the blood) is found to be associated with 1,067 drugs and 1,016 conditions by eHealthMe. Check the latest studies of Hypercalcaemia.



On Jul, 03, 2026

189,425 people reported to have side effects when taking Eliquis.
Among them, 57 people (0.03%) have Hypercalcaemia.

Could Eliquis cause Hypercalcaemia?

Among these 57 people:

What is the gender of people who have Hypercalcaemia when taking Eliquis? *

  • female: 56.25 %
  • male: 43.75 %

What is the age of people who have Hypercalcaemia when taking Eliquis? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 5.13 %
  • 50-59: 10.26 %
  • 60+: 84.62 %

What are other drugs people take besides Eliquis? *

  1. Metformin: 10 people, 17.54%
  2. Morphine: 6 people, 10.53%
  3. Formoterol Fumarate: 6 people, 10.53%
  4. Nadolol: 6 people, 10.53%
  5. Lasix: 6 people, 10.53%
  6. Alvesco: 6 people, 10.53%
  7. Asacol: 6 people, 10.53%
  8. Budesonide: 6 people, 10.53%
  9. Omeprazole: 5 people, 8.77%
  10. Creon: 4 people, 7.02%

What are other side effects people have besides Hypercalcaemia? *

  1. Fatigue (feeling of tiredness): 17 people, 29.82%
  2. Diarrhea: 15 people, 26.32%
  3. Dehydration (dryness resulting from the removal of water): 10 people, 17.54%
  4. Weakness: 8 people, 14.04%
  5. High Blood Pressure: 7 people, 12.28%
  6. Haematochezia (passage of stools containing blood): 6 people, 10.53%
  7. Hyperparathyroidism Primary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium- primary): 6 people, 10.53%
  8. Drowsiness: 6 people, 10.53%
  9. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 6 people, 10.53%
  10. General Physical Health Deterioration (weak health status): 6 people, 10.53%

What are the existing conditions these people have? *

  1. High Blood Pressure: 11 people, 19.30%
  2. Multiple Myeloma (cancer of the plasma cells): 7 people, 12.28%
  3. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 6 people, 10.53%
  4. Colitis (inflammation of colon): 6 people, 10.53%
  5. High Blood Cholesterol: 6 people, 10.53%
  6. Diabetes: 5 people, 8.77%
  7. Lung Neoplasm Malignant (cancer tumour of lung): 4 people, 7.02%
  8. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 5.26%
  9. Depression: 2 people, 3.51%
  10. Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 3.51%

* Approximation only. Some reports may have incomplete information.

Do you take Eliquis and have Hypercalcaemia?

- Check whether Hypercalcaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Eliquis:

Hypercalcaemia treatments and more:

How severe was Hypercalcaemia and when was it recovered:

Expand to all the drugs that have ingredients of apixaban:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Eliquis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypercalcaemia:

Browse all the conditions that are associated with Hypercalcaemia:


How the study uses the data?

The study uses data from the FDA. It is based on apixaban (the active ingredients of Eliquis) and Eliquis (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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