Embeda and Gerd - a phase IV clinical study of FDA data

Summary:

Gerd is reported as a side effect among people who take Embeda (morphine sulfate; naltrexone hydrochloride), especially for people who are male, 40-49 old, have been taking the drug for < 1 month also take Cymbalta, and have Pain.

The phase IV clinical study analyzes which people have Gerd when taking Embeda. It is created by eHealthMe based on reports of 1,394 people who have side effects when taking Embeda from the FDA, and is updated regularly.

What is Embeda?

Embeda has active ingredients of morphine sulfate; naltrexone hydrochloride. eHealthMe is studying from 1,407 Embeda users. Check the latest studies of Embeda.

What is Gerd?

Gerd (gastro-oesophageal reflux disease) is found to be associated with 3,302 drugs and 3,435 conditions by eHealthMe. Check the latest studies of Gerd.

On Jan, 10, 2026

1,394 people reported to have side effects when taking Embeda.
Among them, 11 people (0.79%) have Gerd.

Among these 11 people:

How long have people been on Embeda when they have Gerd? *

What is the gender of people who have Gerd when taking Embeda? *

female: 30 %
male: 70 %

What is the age of people who have Gerd when taking Embeda? *

What are other drugs people take besides Embeda? *

What are other side effects people have besides Gerd? *

Nausea And Vomiting: 4 people, 36.36%
Fatigue (feeling of tiredness): 4 people, 36.36%
Nausea (feeling of having an urge to vomit): 4 people, 36.36%
High Blood Pressure: 3 people, 27.27%
Food Poisoning (poison in food): 2 people, 18.18%
Fungal Nail Infection: 2 people, 18.18%
Gastroenteritis Viral (inflammation of stomach and intestine caused by virus infection): 2 people, 18.18%
Eye Irritation: 2 people, 18.18%
Eating Disorder: 2 people, 18.18%
Hyperhidrosis (abnormally increased sweating): 2 people, 18.18%

What are the existing conditions these people have? *

Pain: 5 people, 45.45%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 27.27%
Restless Leg Syndrome (a powerful urge to move your legs): 3 people, 27.27%
Neuropathy Peripheral (surface nerve damage): 3 people, 27.27%
Glucose Tolerance Impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis): 3 people, 27.27%
High Blood Cholesterol: 3 people, 27.27%
Breakthrough Pain: 2 people, 18.18%
Cystic Fibrosis (disease of the secretary glands): 2 people, 18.18%
Hormone Level Abnormal: 2 people, 18.18%
Mood Swings (an extreme or rapid change in mood): 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Embeda:

Embeda (1,407 reports)

Gerd treatments and more:

Gerd (445,776 reports)

How severe was Gerd and when was it recovered:

Gerd in Embeda

Expand to all the drugs that have ingredients of morphine sulfate; naltrexone hydrochloride:

Gerd and drugs with ingredients of morphine sulfate; naltrexone hydrochloride (8 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Embeda:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Gerd:

Gerd (3,301 drugs)

Browse all the conditions that are associated with Gerd:

Gerd (3,435 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on morphine sulfate; naltrexone hydrochloride (the active ingredients of Embeda) and Embeda (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.