Emsam and Constipation - a phase IV clinical study of FDA data

Summary:

Constipation is reported as a side effect among people who take Emsam (selegiline), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Vitamin D3, and have Stress and anxiety.

The phase IV clinical study analyzes which people have Constipation when taking Emsam. It is created by eHealthMe based on reports of 1,646 people who have side effects when taking Emsam from the FDA, and is updated regularly.

What is Emsam?

Emsam has active ingredients of selegiline. It is often used in depression. eHealthMe is studying from 1,875 Emsam users. Check the latest studies of Emsam.

What is Constipation?

Constipation is found to be associated with 3,005 drugs and 4,590 conditions by eHealthMe. Check the latest studies of Constipation.

On Nov, 15, 2025

1,646 people reported to have side effects when taking Emsam.
Among them, 15 people (0.91%) have Constipation.

Among these 15 people:

How long have people been on Emsam when they have Constipation? *

What is the gender of people who have Constipation when taking Emsam? *

female: 80 %
male: 20 %

What is the age of people who have Constipation when taking Emsam? *

What are other drugs people take besides Emsam? *

What are other side effects people have besides Constipation? *

Weakness: 3 people, 20.00%
Insomnia (sleeplessness): 3 people, 20.00%
Weight Increased: 2 people, 13.33%
Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 2 people, 13.33%
Tremor (trembling or shaking movements in one or more parts of your body): 2 people, 13.33%
Stress And Anxiety: 2 people, 13.33%
High Blood Pressure: 2 people, 13.33%
Dizziness: 2 people, 13.33%
Malaise (a feeling of general discomfort or uneasiness): 2 people, 13.33%
Fatigue (feeling of tiredness): 1 person, 6.67%

What are the existing conditions these people have? *

Stress And Anxiety: 4 people, 26.67%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 13.33%
Sleep Disorder: 1 person, 6.67%
Seasonal Allergy (allergic condition due to certain season): 1 person, 6.67%
Psychotic Disorder: 1 person, 6.67%
Osteoporosis (bones weak and more likely to break): 1 person, 6.67%
Itching: 1 person, 6.67%
Insomnia (sleeplessness): 1 person, 6.67%
High Blood Pressure: 1 person, 6.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Emsam and have Constipation?

- Check whether Constipation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Emsam:

Emsam (1,875 reports)

Constipation treatments and more:

Constipation (337,868 reports)

Browse all side effects of Emsam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Constipation:

Constipation (3,005 drugs)

Browse all the conditions that are associated with Constipation:

Constipation (4,590 conditions)

Drugs similar to Emsam and Constipation :

How the study uses the data?

The study uses data from the FDA. It is based on selegiline (the active ingredients of Emsam) and Emsam (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.