Enbrel and Gallbladder attack - a phase IV clinical study of FDA data

Summary:

Gallbladder attack is reported as a side effect among people who take Enbrel (etanercept), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Folic Acid, and have Psoriatic arthropathy.

The phase IV clinical study analyzes which people have Gallbladder attack when taking Enbrel. It is created by eHealthMe based on reports of 662,905 people who have side effects when taking Enbrel from the FDA, and is updated regularly.

What is Enbrel?

Enbrel has active ingredients of etanercept. It is often used in rheumatoid arthritis. eHealthMe is studying from 664,677 Enbrel users. Check the latest studies of Enbrel.

What is Gallbladder attack?

Gallbladder attack (gallstones, gallbladder disease and gallbladder pain) is found to be associated with 617 drugs and 979 conditions by eHealthMe. Check the latest studies of Gallbladder attack.

On Jan, 26, 2026

662,905 people reported to have side effects when taking Enbrel.
Among them, 37 people (0.01%) have Gallbladder attack.

Among these 37 people:

How long have people been on Enbrel when they have Gallbladder attack? *

What is the gender of people who have Gallbladder attack when taking Enbrel? *

female: 80.56 %
male: 19.44 %

What is the age of people who have Gallbladder attack when taking Enbrel? *

What are other drugs people take besides Enbrel? *

Folic Acid: 5 people, 13.51%
Metoprolol Tartrate: 4 people, 10.81%
Furosemide: 4 people, 10.81%
Niacin: 4 people, 10.81%
Nitroglycerin: 4 people, 10.81%
Calcium: 4 people, 10.81%
Loperamide Hydrochloride: 4 people, 10.81%
Lioresal: 4 people, 10.81%
Ranitidine: 4 people, 10.81%
Lamotrigine: 4 people, 10.81%

What are other side effects people have besides Gallbladder attack? *

Gallstones (stone formation by bile component): 12 people, 32.43%
Abdominal Pain Upper: 4 people, 10.81%
Nosebleed (bleeding from nose): 4 people, 10.81%
Ecchymosis (a discoloration of the skin resulting from bleeding underneath): 4 people, 10.81%
Sinusitis (inflammation of sinus): 3 people, 8.11%
Red Blood Cell Sedimentation Rate Increased: 3 people, 8.11%
Gastrointestinal Infection (infection of stomach and intestine): 3 people, 8.11%
Inflammation: 3 people, 8.11%
Cardiac Failure Congestive: 3 people, 8.11%
Joint Pain: 3 people, 8.11%

What are the existing conditions these people have? *

Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 8 people, 21.62%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 2.70%
Premenstrual Syndrome: 1 person, 2.70%
Premenstrual Dysphoric Disorder: 1 person, 2.70%
Pain: 1 person, 2.70%
Nausea (feeling of having an urge to vomit): 1 person, 2.70%
Mood Swings (an extreme or rapid change in mood): 1 person, 2.70%
Migraine (headache): 1 person, 2.70%
Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 1 person, 2.70%
Juvenile Arthritis (arthritis-related condition that develops in children or teenagers): 1 person, 2.70%

* Approximation only. Some reports may have incomplete information.

Do you take Enbrel and have Gallbladder attack?

- Check whether Gallbladder attack is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Enbrel:

Enbrel (664,677 reports)

Browse all side effects of Enbrel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Gallbladder attack:

Gallbladder attack (617 drugs)

Browse all the conditions that are associated with Gallbladder attack:

Gallbladder attack (979 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on etanercept (the active ingredients of Enbrel) and Enbrel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.