Enbrel and Gerd - a phase IV clinical study of FDA data

Summary:

Gerd is reported as a side effect among people who take Enbrel (etanercept), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Humira, and have Psoriatic arthropathy.

The phase IV clinical study analyzes which people have Gerd when taking Enbrel. It is created by eHealthMe based on reports of 662,905 people who have side effects when taking Enbrel from the FDA, and is updated regularly.

What is Enbrel?

Enbrel has active ingredients of etanercept. It is often used in rheumatoid arthritis. eHealthMe is studying from 664,676 Enbrel users. Check the latest studies of Enbrel.

What is Gerd?

Gerd (gastro-oesophageal reflux disease) is found to be associated with 3,364 drugs and 3,435 conditions by eHealthMe. Check the latest studies of Gerd.

On Oct, 15, 2025

662,905 people reported to have side effects when taking Enbrel.
Among them, 1,959 people (0.3%) have Gerd.

Among these 1,959 people:

* Approximation only. Some reports may have incomplete information.

Do you take Enbrel and have Gerd?

- Check whether Gerd is associated with a drug or a condition (FREE)
- Predict drug outcomes for up to one year with AI (FREE)
- Get an AI agent to monitor your drugs continuously (FREE)

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Enbrel:

Enbrel (664,676 reports)

Gerd treatments and more:

Gerd (445,776 reports)

How severe was Gerd and when was it recovered:

Gerd in Enbrel

Expand to all the drugs that have ingredients of etanercept:

Gerd and drugs with ingredients of etanercept (2,018 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Enbrel side effects:

Browse all side effects of Enbrel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Gerd:

Nexium side effect: Gerd (12,089 reports)
Prednisone side effect: Gerd (8,566 reports)
Aspirin side effect: Gerd (7,706 reports)
Omeprazole side effect: Gerd (7,184 reports)
Fosamax side effect: Gerd (7,170 reports)
Prilosec side effect: Gerd (7,041 reports)
Pantoprazole side effect: Gerd (6,020 reports)
Protonix side effect: Gerd (4,972 reports)
Prevacid side effect: Gerd (4,931 reports)
Lisinopril side effect: Gerd (4,561 reports)

Browse all the drugs that are associated with Gerd:

Gerd (3,364 drugs)

Common conditions associated with Gerd:

Hypertension aggravated: 8,809 reports
Htn: 8,796 reports
Gerds: 8,087 reports
Heartburn: 7,618 reports
Osteoporosis: 6,424 reports
Thin bones: 6,141 reports
Reflux esophagitis: 5,786 reports
Pain exacerbated: 5,547 reports
Pain relief: 5,525 reports
Gastrooesophageal reflux disease: 5,263 reports

Browse all the conditions that are associated with Gerd:

Gerd (3,435 conditions)

Drugs similar to Enbrel and Gerd :

How the study uses the data?

The study uses data from the FDA. It is based on etanercept (the active ingredients of Enbrel) and Enbrel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.