Enbrel and Mononeuropathy - a phase IV clinical study of FDA data

Summary:

Mononeuropathy is reported as a side effect among people who take Enbrel (etanercept), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Actemra, and have Juvenile rheumatoid arthritis.

The phase IV clinical study analyzes which people have Mononeuropathy when taking Enbrel. It is created by eHealthMe based on reports of 662,905 people who have side effects when taking Enbrel from the FDA, and is updated regularly.

What is Enbrel?

Enbrel has active ingredients of etanercept. It is often used in rheumatoid arthritis. eHealthMe is studying from 664,678 Enbrel users. Check the latest studies of Enbrel.

What is Mononeuropathy?

Mononeuropathy (a type of damage to nerves outside the brain and spinal cord) is found to be associated with 64 drugs and 166 conditions by eHealthMe. Check the latest studies of Mononeuropathy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

662,905 people reported to have side effects when taking Enbrel.
Among them, 19 people (0.0%) have Mononeuropathy.

Among these 19 people:

How long have people been on Enbrel when they have Mononeuropathy? *

What is the gender of people who have Mononeuropathy when taking Enbrel? *

female: 88.24 %
male: 11.76 %

What is the age of people who have Mononeuropathy when taking Enbrel? *

What are other drugs people take besides Enbrel? *

What are other side effects people have besides Mononeuropathy? *

Drug Ineffective: 7 people, 36.84%
Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands): 7 people, 36.84%
Neurosarcoidosis (a condition of unknown cause featuring a collection of immune cells in various tissues, involving the central nervous system (brain and spinal cord)): 4 people, 21.05%
Drug Intolerance (drug sensitivity): 4 people, 21.05%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 2 people, 10.53%
Numbness And Tingling (unusual prickling sensations): 2 people, 10.53%
Sinusitis (inflammation of sinus): 2 people, 10.53%
Rheumatoid Vasculitis (inflammation of veins with painful joints and morning stiffness): 2 people, 10.53%
Injection Site Pain: 2 people, 10.53%
Ear Haemorrhage (bleeding from ear): 1 person, 5.26%

What are the existing conditions these people have? *

Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 3 people, 15.79%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 10.53%
Thrombosis (formation of a blood clot inside a blood vessel): 1 person, 5.26%
Sinus Congestion (blockage of sinus): 1 person, 5.26%
Rectal Haemorrhage (bleeding from anus): 1 person, 5.26%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 5.26%
Pharyngeal Oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal): 1 person, 5.26%
Micturition Urgency (urgency to pass the urine): 1 person, 5.26%
Hypersensitivity: 1 person, 5.26%
Headache (pain in head): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Enbrel and have Mononeuropathy?

- Check whether Mononeuropathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Enbrel:

Enbrel (664,678 reports)

Browse all side effects of Enbrel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mononeuropathy:

Mononeuropathy (64 drugs)

Browse all the conditions that are associated with Mononeuropathy:

Mononeuropathy (166 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on etanercept (the active ingredients of Enbrel) and Enbrel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.