Enbrel and Pyogenic granuloma - a phase IV clinical study of FDA data

Summary:

Pyogenic granuloma is reported as a side effect among people who take Enbrel (etanercept), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Prednisone, and have Psoriasis.

The phase IV clinical study analyzes which people have Pyogenic granuloma when taking Enbrel. It is created by eHealthMe based on reports of 662,905 people who have side effects when taking Enbrel from the FDA, and is updated regularly.

What is Enbrel?

Enbrel has active ingredients of etanercept. It is often used in rheumatoid arthritis. eHealthMe is studying from 664,678 Enbrel users. Check the latest studies of Enbrel.

What is Pyogenic granuloma?

Pyogenic granuloma (small, raised, red bumps on the skin) is found to be associated with 94 drugs and 236 conditions by eHealthMe. Check the latest studies of Pyogenic granuloma.



On Jul, 27, 2026

662,905 people reported to have side effects when taking Enbrel.
Among them, 13 people (0.0%) have Pyogenic granuloma.

Could Enbrel cause Pyogenic granuloma?

Among these 13 people:

How long have people been on Enbrel when they have Pyogenic granuloma? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 20 %
  • 1 - 2 years: 20 %
  • 2 - 5 years: 20 %
  • 5 - 10 years: 20 %
  • 10+ years: 20 %

What is the gender of people who have Pyogenic granuloma when taking Enbrel? *

  • female: 61.54 %
  • male: 38.46 %

What is the age of people who have Pyogenic granuloma when taking Enbrel? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 11.11 %
  • 20-29: 11.11 %
  • 30-39: 11.11 %
  • 40-49: 22.22 %
  • 50-59: 0.0 %
  • 60+: 44.44 %

What are other drugs people take besides Enbrel? *

  1. Prednisone: 3 people, 23.08%
  2. Zometa: 2 people, 15.38%
  3. Hydrocodone: 2 people, 15.38%
  4. Humira: 2 people, 15.38%
  5. Augmentin: 2 people, 15.38%
  6. Methotrexate: 2 people, 15.38%
  7. Klonopin: 1 person, 7.69%
  8. Glucophage: 1 person, 7.69%
  9. Gentamicin: 1 person, 7.69%
  10. Gabapentin: 1 person, 7.69%

What are other side effects people have besides Pyogenic granuloma? *

  1. Rashes (redness): 3 people, 23.08%
  2. Nail Bed Bleeding: 2 people, 15.38%
  3. Bone Disorder: 2 people, 15.38%
  4. Emotional Distress: 2 people, 15.38%
  5. Dyspnea (difficult or laboured breathing): 2 people, 15.38%
  6. Osteonecrosis Of Jaw (death of bone of jaw): 2 people, 15.38%
  7. Osteomyelitis (infection of bone): 2 people, 15.38%
  8. Fall: 2 people, 15.38%
  9. Deformity (disfigurement): 2 people, 15.38%
  10. Febrile Neutropenia (fever with reduced white blood cells): 2 people, 15.38%

What are the existing conditions these people have? *

  1. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 23.08%
  2. Psoriasis (immune-mediated disease that affects the skin): 3 people, 23.08%
  3. Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 2 people, 15.38%
  4. Lumbar Spinal Stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone): 1 person, 7.69%
  5. Breast Cancer Metastatic: 1 person, 7.69%
  6. Breast Cancer: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Enbrel and have Pyogenic granuloma?

- Check whether Pyogenic granuloma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Enbrel:

Pyogenic granuloma treatments and more:

How severe was Pyogenic granuloma and when was it recovered:

Expand to all the drugs that have ingredients of etanercept:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Enbrel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pyogenic granuloma:

Browse all the conditions that are associated with Pyogenic granuloma:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on etanercept (the active ingredients of Enbrel) and Enbrel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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