Enbrel and Sinus polyp - a phase IV clinical study of FDA data

Summary:

Sinus polyp is reported as a side effect among people who take Enbrel (etanercept), especially for people who are male, 60+ old, have been taking the drug for 6 - 12 months also take Humira, and have Psoriasis.

The phase IV clinical study analyzes which people have Sinus polyp when taking Enbrel. It is created by eHealthMe based on reports of 662,905 people who have side effects when taking Enbrel from the FDA, and is updated regularly.

What is Enbrel?

Enbrel has active ingredients of etanercept. It is often used in rheumatoid arthritis. eHealthMe is studying from 664,678 Enbrel users. Check the latest studies of Enbrel.

What is Sinus polyp?

Sinus polyp (abnormal tissue growths that grow inside the nasal passages and sinuses) is found to be associated with 201 drugs and 214 conditions by eHealthMe. Check the latest studies of Sinus polyp.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 30, 2026

662,905 people reported to have side effects when taking Enbrel.
Among them, 35 people (0.01%) have Sinus polyp.

Could Enbrel cause Sinus polyp?

Among these 35 people:

How long have people been on Enbrel when they have Sinus polyp? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 28.57 %
  • 6 - 12 months: 28.57 %
  • 1 - 2 years: 14.29 %
  • 2 - 5 years: 14.29 %
  • 5 - 10 years: 14.29 %
  • 10+ years: 0.0 %

What is the gender of people who have Sinus polyp when taking Enbrel? *

  • female: 48.57 %
  • male: 51.43 %

What is the age of people who have Sinus polyp when taking Enbrel? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 4.17 %
  • 20-29: 4.17 %
  • 30-39: 0.0 %
  • 40-49: 33.33 %
  • 50-59: 20.83 %
  • 60+: 37.5 %

What are other drugs people take besides Enbrel? *

  1. Actonel: 2 people, 5.71%
  2. Tylenol: 2 people, 5.71%
  3. Simvastatin: 2 people, 5.71%
  4. Flonase: 2 people, 5.71%
  5. Humira: 2 people, 5.71%
  6. Ibuprofen: 1 person, 2.86%
  7. Actos: 1 person, 2.86%
  8. Amlodipine: 1 person, 2.86%
  9. Aspirin: 1 person, 2.86%
  10. Crestor: 1 person, 2.86%

What are other side effects people have besides Sinus polyp? *

  1. Sinusitis (inflammation of sinus): 20 people, 57.14%
  2. Pneumonia: 4 people, 11.43%
  3. Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 11.43%
  4. Malaise (a feeling of general discomfort or uneasiness): 3 people, 8.57%
  5. Paranasal Sinus Neoplasm (paranasal sinus tumour): 3 people, 8.57%
  6. Sinus Disorder (disease of sinus): 3 people, 8.57%
  7. Tooth Fracture: 3 people, 8.57%
  8. Tooth Abscess (pus formation in tooth): 3 people, 8.57%
  9. Gastroenteritis (inflammation of stomach and intestine): 3 people, 8.57%
  10. Psoriasis (immune-mediated disease that affects the skin): 3 people, 8.57%

What are the existing conditions these people have? *

  1. Psoriasis (immune-mediated disease that affects the skin): 5 people, 14.29%
  2. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 4 people, 11.43%
  3. Juvenile Arthritis (arthritis-related condition that develops in children or teenagers): 1 person, 2.86%
  4. Glaucoma (increased fluid pressure in the eye with vision loss): 1 person, 2.86%
  5. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 2.86%

* Approximation only. Some reports may have incomplete information.

Do you take Enbrel and have Sinus polyp?

- Check whether Sinus polyp is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Enbrel:

Sinus polyp treatments and more:

How severe was Sinus polyp and when was it recovered:

Expand to all the drugs that have ingredients of etanercept:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Enbrel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sinus polyp:

Browse all the conditions that are associated with Sinus polyp:


How the study uses the data?

The study uses data from the FDA. It is based on etanercept (the active ingredients of Enbrel) and Enbrel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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