Enbrel and Vaginal bleeding between periods - a phase IV clinical study of FDA data

Summary:

Vaginal bleeding between periods is reported as a side effect among people who take Enbrel (etanercept), especially for people who are 30-39 old, have been taking the drug for 1 - 6 months also take Methotrexate, and have Psoriasis.

The phase IV clinical study analyzes which people have Vaginal bleeding between periods when taking Enbrel. It is created by eHealthMe based on reports of 662,905 people who have side effects when taking Enbrel from the FDA, and is updated regularly.

What is Enbrel?

Enbrel has active ingredients of etanercept. It is often used in rheumatoid arthritis. eHealthMe is studying from 664,678 Enbrel users. Check the latest studies of Enbrel.

What is Vaginal bleeding between periods?

Vaginal bleeding between periods is found to be associated with 577 drugs and 1,466 conditions by eHealthMe. Check the latest studies of Vaginal bleeding between periods.

On Jul, 10, 2026

662,905 people reported to have side effects when taking Enbrel.
Among them, 93 people (0.01%) have Vaginal bleeding between periods.

Could Enbrel cause Vaginal bleeding between periods?

Among these 93 people:

How long have people been on Enbrel when they have Vaginal bleeding between periods? *

What is the age of people who have Vaginal bleeding between periods when taking Enbrel? *

What are other drugs people take besides Enbrel? *

What are other side effects people have besides Vaginal bleeding between periods? *

Heavy Or Prolong Menstrual Bleeding: 15 people, 16.13%
Dysmenorrhea (painful menstruation): 8 people, 8.60%
Joint Pain: 7 people, 7.53%
Vaginal Bleeding: 7 people, 7.53%
Menstrual Disorder (disease of menstrual cycle): 6 people, 6.45%
Menstruation Irregular: 6 people, 6.45%
Pain In Extremity: 5 people, 5.38%
Drug Ineffective: 5 people, 5.38%
Injection Site Erythema (redness at injection site): 4 people, 4.30%
Muscle Spasms (muscle contraction): 4 people, 4.30%

What are the existing conditions these people have? *

Psoriasis (immune-mediated disease that affects the skin): 18 people, 19.35%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 8 people, 8.60%
Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 3 people, 3.23%
Birth Control: 3 people, 3.23%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 2.15%
Uveitis (inflammation of the uvea): 1 person, 1.08%
Sarcoma Metastatic (rare cancers that develop in the muscle, bone, nerves, cartilage, tendons, blood vessels and the fatty and fibrous tissues spreads to other parts): 1 person, 1.08%
Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands): 1 person, 1.08%
Juvenile Arthritis (arthritis-related condition that develops in children or teenagers): 1 person, 1.08%
High Blood Pressure: 1 person, 1.08%

* Approximation only. Some reports may have incomplete information.

Do you take Enbrel and have Vaginal bleeding between periods?

- Check whether Vaginal bleeding between periods is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Enbrel:

Enbrel (664,678 reports)

Browse all side effects of Enbrel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Vaginal bleeding between periods:

Vaginal bleeding between periods (577 drugs)

Browse all the conditions that are associated with Vaginal bleeding between periods:

Vaginal bleeding between periods (1,466 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on etanercept (the active ingredients of Enbrel) and Enbrel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.