Entresto and Red blood cell count increased - a phase IV clinical study of FDA data

Summary:

Red blood cell count increased is reported as a side effect among people who take Entresto (sacubitril; valsartan), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Jardiance, and have Cardiac failure chronic.

The phase IV clinical study analyzes which people have Red blood cell count increased when taking Entresto. It is created by eHealthMe based on reports of 126,188 people who have side effects when taking Entresto from the FDA, and is updated regularly.

What is Entresto?

Entresto has active ingredients of sacubitril; valsartan. eHealthMe is studying from 126,629 Entresto users. Check the latest studies of Entresto.

What is Red blood cell count increased?

Red blood cell count increased is found to be associated with 429 drugs and 588 conditions by eHealthMe. Check the latest studies of Red blood cell count increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

126,188 people reported to have side effects when taking Entresto.
Among them, 16 people (0.01%) have Red blood cell count increased.

Could Entresto cause Red blood cell count increased?

Among these 16 people:

How long have people been on Entresto when they have Red blood cell count increased? *

What is the gender of people who have Red blood cell count increased when taking Entresto? *

female: 25 %
male: 75 %

What is the age of people who have Red blood cell count increased when taking Entresto? *

What are other drugs people take besides Entresto? *

What are other side effects people have besides Red blood cell count increased? *

Haemoglobin Increased: 6 people, 37.50%
Dizziness: 5 people, 31.25%
Haemoglobin Decreased: 3 people, 18.75%
Weight Decreased: 3 people, 18.75%
Glycosylated Haemoglobin Decreased: 3 people, 18.75%
Dyspnea (difficult or laboured breathing): 3 people, 18.75%
Blood Urea Increased: 3 people, 18.75%
Hypotension (abnormally low blood pressure): 3 people, 18.75%
Blood Creatinine Increased: 3 people, 18.75%
Blood Calcium Decreased: 2 people, 12.50%

What are the existing conditions these people have? *

Cardiac Failure Congestive: 2 people, 12.50%
Cardiac Failure Chronic: 2 people, 12.50%
Oedema Due To Cardiac Disease (fluid collection in tissue due to heart disease): 1 person, 6.25%
Hypotension (abnormally low blood pressure): 1 person, 6.25%
High Blood Pressure: 1 person, 6.25%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 6.25%
Cardiomyopathy (weakening of the heart muscle): 1 person, 6.25%
Cardiac Failure: 1 person, 6.25%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Entresto and have Red blood cell count increased?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Entresto:

Entresto (126,629 reports)

Browse all side effects of Entresto:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Red blood cell count increased:

Red blood cell count increased (429 drugs)

Browse all the conditions that are associated with Red blood cell count increased:

Red blood cell count increased (588 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sacubitril; valsartan (the active ingredients of Entresto) and Entresto (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.