Enulose and Paraesthesia - a phase IV clinical study of FDA data

Summary:

Paraesthesia is reported as a side effect among people who take Enulose (lactulose), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Oxycontin, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Paraesthesia when taking Enulose. It is created by eHealthMe based on reports of 703 people who have side effects when taking Enulose from the FDA, and is updated regularly.

What is Enulose?

Enulose has active ingredients of lactulose. It is often used in constipation. eHealthMe is studying from 711 Enulose users. Check the latest studies of Enulose.

What is Paraesthesia?

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect) is found to be associated with 2,689 drugs and 3,120 conditions by eHealthMe. Check the latest studies of Paraesthesia.

On Aug, 10, 2026

703 people reported to have side effects when taking Enulose.
Among them, 16 people (2.28%) have Paraesthesia.

Among these 16 people:

How long have people been on Enulose when they have Paraesthesia? *

What is the gender of people who have Paraesthesia when taking Enulose? *

female: 87.5 %
male: 12.5 %

What is the age of people who have Paraesthesia when taking Enulose? *

What are other drugs people take besides Enulose? *

What are other side effects people have besides Paraesthesia? *

Nausea (feeling of having an urge to vomit): 7 people, 43.75%
Hypoaesthesia (reduced sense of touch or sensation): 7 people, 43.75%
Back Pain: 7 people, 43.75%
Fatigue (feeling of tiredness): 5 people, 31.25%
Chest Pain: 5 people, 31.25%
Weakness: 5 people, 31.25%
Pain In Extremity: 5 people, 31.25%
Muscle Spasms (muscle contraction): 4 people, 25.00%
Joint Pain: 4 people, 25.00%
Insomnia (sleeplessness): 4 people, 25.00%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 4 people, 25.00%
Parkinson's Disease: 2 people, 12.50%
Nausea (feeling of having an urge to vomit): 2 people, 12.50%
Metastases To Bone (cancer spreads to bone): 2 people, 12.50%
Chest Pain: 2 people, 12.50%
Back Pain: 2 people, 12.50%
Asthma: 2 people, 12.50%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 6.25%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 6.25%
Oral Candidiasis (fungal infection of mouth): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Enulose and have Paraesthesia?

- Check whether Paraesthesia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Enulose:

Enulose (711 reports)

Paraesthesia treatments and more:

Paraesthesia (184,215 reports)

Browse all side effects of Enulose:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Paraesthesia:

Paraesthesia (2,690 drugs)

Browse all the conditions that are associated with Paraesthesia:

Paraesthesia (3,120 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lactulose (the active ingredients of Enulose) and Enulose (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.