Enzalutamide and Hypercalcaemia - a phase IV clinical study of FDA data

Summary:

Hypercalcaemia is reported as a side effect among people who take Enzalutamide (enzalutamide), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Eliquis, and have Prostate cancer.

The phase IV clinical study analyzes which people have Hypercalcaemia when taking Enzalutamide. It is created by eHealthMe based on reports of 14,017 people who have side effects when taking Enzalutamide from the FDA, and is updated regularly.

What is Enzalutamide?

Enzalutamide has active ingredients of enzalutamide. eHealthMe is studying from 14,018 Enzalutamide users. Check the latest studies of Enzalutamide.

What is Hypercalcaemia?

Hypercalcaemia (elevated calcium (ca+) level in the blood) is found to be associated with 1,061 drugs and 1,017 conditions by eHealthMe. Check the latest studies of Hypercalcaemia.



On Jul, 19, 2026

14,017 people reported to have side effects when taking Enzalutamide.
Among them, 13 people (0.09%) have Hypercalcaemia.

Could Enzalutamide cause Hypercalcaemia?

Among these 13 people:

How long have people been on Enzalutamide when they have Hypercalcaemia? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 20 %
  • 1 - 2 years: 10 %
  • 2 - 5 years: 10 %
  • 5 - 10 years: 10 %
  • 10+ years: 0.0 %

What is the gender of people who have Hypercalcaemia when taking Enzalutamide? *

  • female: 7.69 %
  • male: 92.31 %

What is the age of people who have Hypercalcaemia when taking Enzalutamide? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 12.5 %
  • 60+: 87.5 %

What are other drugs people take besides Enzalutamide? *

  1. Xgeva: 2 people, 15.38%
  2. Eligard: 2 people, 15.38%
  3. Eliquis: 2 people, 15.38%
  4. Zytiga: 1 person, 7.69%
  5. Leuprolide Acetate: 1 person, 7.69%
  6. Allopurinol: 1 person, 7.69%
  7. Ativan: 1 person, 7.69%
  8. Fish Oil: 1 person, 7.69%
  9. Flaxseed: 1 person, 7.69%
  10. Harvoni: 1 person, 7.69%

What are other side effects people have besides Hypercalcaemia? *

  1. Fall: 5 people, 38.46%
  2. Septic Embolus (a type of embolism that is infected with bacteria): 4 people, 30.77%
  3. Sepsis (a severe blood infection that can lead to organ failure and death): 4 people, 30.77%
  4. Weakness: 4 people, 30.77%
  5. Urinary Tract Infection: 3 people, 23.08%
  6. Burkitt Lymphoma (cancer of the lymphatic system): 3 people, 23.08%
  7. Prostate Cancer Metastatic: 2 people, 15.38%
  8. Confusional State: 2 people, 15.38%
  9. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 7.69%
  10. Blood Parathyroid Hormone Decreased: 1 person, 7.69%

What are the existing conditions these people have? *

  1. Prostate Cancer: 8 people, 61.54%
  2. Prostate Cancer Metastatic: 3 people, 23.08%
  3. Metastases To Bone (cancer spreads to bone): 2 people, 15.38%
  4. Stress And Anxiety: 1 person, 7.69%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.69%
  6. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 7.69%
  7. Breast Cancer: 1 person, 7.69%
  8. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 7.69%
  9. Cough: 1 person, 7.69%
  10. Depression: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Enzalutamide and have Hypercalcaemia?

- Check whether Hypercalcaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Enzalutamide:

Hypercalcaemia treatments and more:

How severe was Hypercalcaemia and when was it recovered:

Expand to all the drugs that have ingredients of enzalutamide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Enzalutamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypercalcaemia:

Browse all the conditions that are associated with Hypercalcaemia:


How the study uses the data?

The study uses data from the FDA. It is based on enzalutamide (the active ingredients of Enzalutamide) and Enzalutamide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: